Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50040181
TargetCasein kinase I isoform gamma-2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390500(CHEMBL2071614)
Affinity DataIC50: 700nMAssay Description:Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390497(CHEMBL2071611)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of CK1delta by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390496(CHEMBL2071610)
Affinity DataIC50: 1.17E+3nMAssay Description:Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390497(CHEMBL2071611)
Affinity DataIC50: 1.45E+3nMAssay Description:Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390498(CHEMBL2071612)
Affinity DataIC50: 1.51E+3nMAssay Description:Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase I isoform delta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390496(CHEMBL2071610)
Affinity DataIC50: 1.63E+3nMAssay Description:Inhibition of CK1delta by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390506(CHEMBL2071624)
Affinity DataIC50: 1.66E+3nMAssay Description:Inhibition of CK1delta by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390501(CHEMBL2071615)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of CK1delta by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390495(CHEMBL2071609)
Affinity DataIC50: 2.18E+3nMAssay Description:Inhibition of CK1delta by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390500(CHEMBL2071614)
Affinity DataIC50: 2.32E+3nMAssay Description:Inhibition of CK1delta by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390503(CHEMBL2071618)
Affinity DataIC50: 2.34E+3nMAssay Description:Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390505(CHEMBL2071623)
Affinity DataIC50: 2.37E+3nMAssay Description:Inhibition of CK1delta by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390498(CHEMBL2071612)
Affinity DataIC50: 2.62E+3nMAssay Description:Inhibition of CK1delta by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390503(CHEMBL2071618)
Affinity DataIC50: 2.88E+3nMAssay Description:Inhibition of CK1delta by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390507(CHEMBL2071625)
Affinity DataIC50: 3.17E+3nMAssay Description:Inhibition of CK1delta by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390494(CHEMBL2071608)
Affinity DataIC50: 3.17E+3nMAssay Description:Inhibition of CK1delta by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390497(CHEMBL2071611)
Affinity DataIC50: 3.54E+3nMAssay Description:Inhibition of CK1alpha by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390499(CHEMBL2071613)
Affinity DataIC50: 3.61E+3nMAssay Description:Inhibition of CK1delta by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390506(CHEMBL2071624)
Affinity DataIC50: 3.83E+3nMAssay Description:Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390504(CHEMBL2071622)
Affinity DataIC50: 3.97E+3nMAssay Description:Inhibition of CK1delta by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390502(CHEMBL2071616)
Affinity DataIC50: 4.37E+3nMAssay Description:Inhibition of CK1delta by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390499(CHEMBL2071613)
Affinity DataIC50: 4.54E+3nMAssay Description:Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390496(CHEMBL2071610)
Affinity DataIC50: 4.67E+3nMAssay Description:Inhibition of CK1alpha by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390495(CHEMBL2071609)
Affinity DataIC50: 4.89E+3nMAssay Description:Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390495(CHEMBL2071609)
Affinity DataIC50: 5.49E+3nMAssay Description:Inhibition of CK1alpha by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform delta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM124350(CHEMBL2071607 | US8759532, 1)
Affinity DataIC50: 5.77E+3nMAssay Description:Inhibition of CK1delta by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM124350(CHEMBL2071607 | US8759532, 1)
Affinity DataIC50: 6.56E+3nMAssay Description:Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase I isoform alpha(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390498(CHEMBL2071612)
Affinity DataIC50: 7.58E+3nMAssay Description:Inhibition of CK1alpha by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390494(CHEMBL2071608)
Affinity DataIC50: 8.82E+3nMAssay Description:Inhibition of CK1alpha by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390507(CHEMBL2071625)
Affinity DataIC50: 9.10E+3nMAssay Description:Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390500(CHEMBL2071614)
Affinity DataIC50: 9.18E+3nMAssay Description:Inhibition of CK1alpha by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390501(CHEMBL2071615)
Affinity DataIC50: 1.01E+4nMAssay Description:Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM124350(CHEMBL2071607 | US8759532, 1)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of CK1alpha by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390504(CHEMBL2071622)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform gamma-2(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390505(CHEMBL2071623)
Affinity DataIC50: 1.49E+4nMAssay Description:Inhibition of CK1gamma2 expressed in HEK293 cells assessed as inhibition of LRP6 Thr1479 phosphorylation by immunoblottingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetCasein kinase I isoform alpha(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390499(CHEMBL2071613)
Affinity DataIC50: 1.97E+4nMAssay Description:Inhibition of CK1alpha by Lance assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390496(CHEMBL2071610)
Affinity DataIC50: 2.42E+4nMAssay Description:Inhibition of GSK3beta by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390499(CHEMBL2071613)
Affinity DataIC50: 3.01E+4nMAssay Description:Inhibition of GSK3beta by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390495(CHEMBL2071609)
Affinity DataIC50: 3.08E+4nMAssay Description:Inhibition of GSK3beta by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM124350(CHEMBL2071607 | US8759532, 1)
Affinity DataIC50: 3.08E+4nMAssay Description:Inhibition of GSK3beta by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390498(CHEMBL2071612)
Affinity DataIC50: 4.45E+4nMAssay Description:Inhibition of GSK3beta by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50390500(CHEMBL2071614)
Affinity DataIC50: 6.00E+4nMAssay Description:Inhibition of GSK3beta by AlphaScreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMed