Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50001334
TargetBifunctional purine biosynthesis protein ATIC(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520(2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-5...)
Affinity DataIC50: 700nMAssay Description:Hexaglutamyl homologue inhibition activity against the AICAR formyltransferase was determined against MOLT-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Mouse)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520(2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-5...)
Affinity DataIC50: 700nMAssay Description:Hexaglutamyl homologue inhibition activity against the AICAR formyltransferase was determined against L cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Mouse)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520(2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-5...)
Affinity DataIC50: 1.90E+3nMAssay Description:Triglutamyl homologue inhibition activity against AICAR formyltransferase was determined against L cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Mouse)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520(2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-5...)
Affinity DataIC50: 1.90E+3nMAssay Description:Triglutamyl homologue inhibition activity against AICAR formyltransferase was determined against L cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014844(CHEMBL153550 | 2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dih...)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition activity against Glycinamide ribonucleotide transformylase (GAR-TFase) from L cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014843(CHEMBL152172 | 2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dih...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition activity against Glycinamide ribonucleotide transformylase (GAR-TFase) against L cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTrifunctional purine biosynthetic protein adenosine-3(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014843(CHEMBL152172 | 2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dih...)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition activity against Glycinamide ribonucleotide transformylase (GAR-TFase) against L cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Mouse)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014844(CHEMBL153550 | 2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dih...)
Affinity DataIC50: 6.80E+4nMAssay Description:Inhibition activity against AICAR formyltransferase from hog liverMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Human)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520(2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-5...)
Affinity DataIC50: 9.40E+4nMAssay Description:Inhibition activity against AICAR formyltransferase determined against MOLT-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Mouse)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50005520(2-{4-[3-(2,4-Diamino-6-oxo-1,6-dihydro-pyrimidin-5...)
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition activity against AICAR formyltransferase determined against L cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Mouse)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014843(CHEMBL152172 | 2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dih...)
Affinity DataIC50: 2.80E+5nMAssay Description:Inhibition activity against AICAR formyltransferase determined against L cellMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetBifunctional purine biosynthesis protein ATIC(Mouse)
Wellcome Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50014843(CHEMBL152172 | 2-(4-{[3-(2,4-Diamino-6-oxo-1,6-dih...)
Affinity DataIC50: 5.74E+5nMAssay Description:Inhibition activity against AICAR formyltransferase determined against MOLT-4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed