Compile Data Set for Download or QSAR
Report error Found 37 Enz. Inhib. hit(s) with all data for entry = 50040453
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394437(CHEMBL2159084)
Affinity DataIC50: 114nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394435(CHEMBL2159638)
Affinity DataIC50: 118nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394439(CHEMBL2159082)
Affinity DataIC50: 125nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394430(CHEMBL2158890)
Affinity DataIC50: 150nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxy-4-(trifluoromethyl) coumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394432(CHEMBL2159646)
Affinity DataIC50: 165nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394442(CHEMBL2159075)
Affinity DataIC50: 229nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394438(CHEMBL2159083)
Affinity DataIC50: 249nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394440(CHEMBL2159076)
Affinity DataIC50: 275nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394424(CHEMBL2159071)
Affinity DataIC50: 280nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394430(CHEMBL2158890)
Affinity DataIC50: 308nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394429(CHEMBL2158892)
Affinity DataIC50: 349nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394431(CHEMBL2159647)
Affinity DataIC50: 379nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394422(CHEMBL2159073)
Affinity DataIC50: 385nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394441(CHEMBL1578968)
Affinity DataIC50: 403nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394434(CHEMBL2159644)
Affinity DataIC50: 448nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394428(CHEMBL2158893)
Affinity DataIC50: 655nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50052665(Adamantane-1-carboxylic acid (pyridin-3-ylmethyl)-...)
Affinity DataIC50: 676nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394433(CHEMBL2159645)
Affinity DataIC50: 679nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394426(CHEMBL2159069)
Affinity DataIC50: 1.08E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394423(CHEMBL2159072)
Affinity DataIC50: 1.55E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394424(CHEMBL2159071)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxyquinoline as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394436(CHEMBL2159085)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394421(CHEMBL2159074)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394427(CHEMBL2159066)
Affinity DataIC50: 2.88E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target11-beta-hydroxysteroid dehydrogenase 1(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394425(CHEMBL2159070)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of human 11beta-HSD1 expressed in HEK293 cells assessed as conversion of [3H]cortisone to [3H]cortisol after 2 hrs by scintillation counti...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394424(CHEMBL2159071)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394424(CHEMBL2159071)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxy-4-(trifluoromethyl) coumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394442(CHEMBL2159075)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxy-4-(trifluoromethyl) coumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394437(CHEMBL2159084)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxyquinoline as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394437(CHEMBL2159084)
Affinity DataIC50: 1.90E+4nMAssay Description:Inhibition of human CYP3A4 using 7-benzyloxy-4-(trifluoromethyl) coumarin as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394424(CHEMBL2159071)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394424(CHEMBL2159071)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394437(CHEMBL2159084)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394437(CHEMBL2159084)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394437(CHEMBL2159084)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394437(CHEMBL2159084)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
University of Bath

Curated by ChEMBL
LigandPNGBDBM50394424(CHEMBL2159071)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed