Compile Data Set for Download or QSAR
Report error Found 43 Enz. Inhib. hit(s) with all data for entry = 50042806
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM8434(4-[(5Z)-5-{[5-(4-bromophenyl)furan-2-yl]methyliden...)
Affinity DataIC50: 200nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431315(CHEMBL2349206)
Affinity DataIC50: 200nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431310(CHEMBL2349212)
Affinity DataIC50: 300nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431329(CHEMBL2348833)
Affinity DataIC50: 300nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431322(CHEMBL2346710)
Affinity DataKi:  340nMAssay Description:Competitive inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by Lineweaver-Burk plo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431324(CHEMBL2348837)
Affinity DataIC50: 350nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431326(CHEMBL1688850)
Affinity DataIC50: 350nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431321(CHEMBL2348839)
Affinity DataIC50: 500nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431323(CHEMBL2348838)
Affinity DataIC50: 500nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431300(CHEMBL2349219)
Affinity DataIC50: 500nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431314(CHEMBL2349207)
Affinity DataIC50: 500nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431313(CHEMBL2349208)
Affinity DataIC50: 500nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431328(CHEMBL2348834)
Affinity DataIC50: 500nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431322(CHEMBL2346710)
Affinity DataIC50: 650nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431303(CHEMBL2349217)
Affinity DataIC50: 650nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431318(CHEMBL2349203)
Affinity DataIC50: 750nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431325(CHEMBL2348836)
Affinity DataIC50: 750nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431330(CHEMBL2348832)
Affinity DataIC50: 750nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431306(CHEMBL2349215)
Affinity DataIC50: 800nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431320(CHEMBL2349201)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431327(CHEMBL2348835)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431331(CHEMBL2348831)
Affinity DataIC50: 1.25E+3nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431305(CHEMBL2349216)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431302(CHEMBL2349218)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431312(CHEMBL2349210)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431307(CHEMBL2349214)
Affinity DataIC50: 2.50E+3nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM28846(2-[(5Z)-5-{[5-(4-bromophenyl)furan-2-yl]methyliden...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431311(CHEMBL2349211)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431309(CHEMBL2349213)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431319(CHEMBL2349202)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431296(CHEMBL2348828)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431295(CHEMBL2348829)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431294(CHEMBL274480)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM8436(2-[(5Z)-5-(furan-2-ylmethylidene)-4-oxo-2-sulfanyl...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431317(CHEMBL2349204)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431316(CHEMBL2349220)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431308(CHEMBL2349221)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50679(cid_1591868 | SMR000378042 | MLS001005166 | (5Z)-5...)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431298(CHEMBL2348826)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431297(CHEMBL2348827)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431304(CHEMBL1916996)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431332(CHEMBL2348830)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 5(Human)
Nas of Ukraine

Curated by ChEMBL
LigandPNGBDBM50431301(CHEMBL2348825)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human ASK1 using MBP as substrate incubated for 10 mins prior to ATP addition measured after 20 mins by liquid scintillation counting a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed