Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 8368
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
National University of Mexico City

LigandPNGBDBM243079(17-Oxaandrost-5-ene-3β-yl-p-fluorobenzoate (2...)
Affinity DataIC50: 3.58nMAssay Description:The activity of the isozyme 5α-R type 2 was assayed as previously described [Hirosumi et al., J. Steroid Biochem. Mol. Biol., 52:357-363; Bratoe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
National University of Mexico City

LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50: 8.5nMAssay Description:The activity of the isozyme 5α-R type 2 was assayed as previously described [Hirosumi et al., J. Steroid Biochem. Mol. Biol., 52:357-363; Bratoe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
National University of Mexico City

LigandPNGBDBM243088(17-Chloro-16-formylandrost-5,16-diene-3β-yl-p...)
Affinity DataIC50: 550nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
National University of Mexico City

LigandPNGBDBM50334788((17beta-(N-tert-butylcarbamoyl)-4-aza-5alpha-andro...)
Affinity DataIC50: 630nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
National University of Mexico City

LigandPNGBDBM243084(17-Chloro-16-formylandrost-5,16-diene-3β-yl-b...)
Affinity DataIC50: 650nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
National University of Mexico City

LigandPNGBDBM243085(17-Chloro-16-formylandrost-5,16-diene-3β-yl-p...)
Affinity DataIC50: 700nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
National University of Mexico City

LigandPNGBDBM243081(17-Oxaandrost-5-ene-3β-yl-p-bromobenzoate (4))
Affinity DataIC50: 800nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
National University of Mexico City

LigandPNGBDBM243082(17-Oxaandrost-5-ene-3β-yl-p-iodobenzoate (5))
Affinity DataIC50: 800nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
National University of Mexico City

LigandPNGBDBM243087(17-Chloro-16-formylandros-5,16-diene-3β-yl-p-...)
Affinity DataIC50: 800nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
National University of Mexico City

LigandPNGBDBM243079(17-Oxaandrost-5-ene-3β-yl-p-fluorobenzoate (2...)
Affinity DataIC50: 900nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
National University of Mexico City

LigandPNGBDBM243086(17-Chloro-16-formylandrost-5,16-diene-3β-yl-p...)
Affinity DataIC50: 900nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
National University of Mexico City

LigandPNGBDBM243089(17-Chloro-16-formylandrost-5,16-diene-3β-yl-p...)
Affinity DataIC50: 900nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
National University of Mexico City

LigandPNGBDBM243078(17-Oxaandrost-5-ene-3β-yl-benzoate (1))
Affinity DataIC50: 1.00E+3nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
National University of Mexico City

LigandPNGBDBM243080(17-Oxaandrost-5-ene-3β-yl-p-chlorobenzoate (3...)
Affinity DataIC50: 5.00E+3nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Human)
National University of Mexico City

LigandPNGBDBM243083(17-Oxaandrost-5-ene-3β−yl-p-methylbenzo...)
Affinity DataIC50: 5.00E+3nMpH: 7.5Assay Description:The activity of the 5α-R type 1 isozyme was determined by following the conversion of T to DHT at pH 7.5. 2 nM of [1,2,6,7 3H] T, and different ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Human)
National University of Mexico City

LigandPNGBDBM243078(17-Oxaandrost-5-ene-3β-yl-benzoate (1))
Affinity DataIC50: 1.00E+5nMAssay Description:The activity of the isozyme 5α-R type 2 was assayed as previously described [Hirosumi et al., J. Steroid Biochem. Mol. Biol., 52:357-363; Bratoe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/21/2017
Entry Details Article
PubMed