Compile Data Set for Download or QSAR
Report error Found 21 Enz. Inhib. hit(s) with all data for entry = 50040639
TargetCalcium-dependent protein kinase 4(Plasmodium falciparum (isolate 3D7))
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50383381(CHEMBL2070050 | CHEMBL2030554 | US9765037, Compoun...)
Affinity DataIC50: 4nMAssay Description:Inhibition of CDPK4 in Plasmodium falciparum 3D7 microgametesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50397589(CHEMBL2171517)
Affinity DataIC50: 5nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetcGMP-dependent protein kinase(malaria parasite P. falciparum)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50168171(4-[2-(4-Fluoro-phenyl)-5-(1-methyl-piperidin-4-yl)...)
Affinity DataIC50: 8nMAssay Description:Inhibition of PKG in Plasmodium falciparum 3D7 microgametesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 10nMAssay Description:Inhibition of PI3KalphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase mTOR(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 10nMAssay Description:Inhibition of mTORMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 10nMAssay Description:Inhibition of PI3KgammaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 10nMAssay Description:Inhibition of PI3KbetaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM92862(mTOR Inhibitor, BEZ235 | US9284315, BEZ-235)
Affinity DataIC50: 10nMAssay Description:Inhibition of PI3KdeltaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50397590(CHEMBL2171516)
Affinity DataIC50: 20nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50397588(CHEMBL2171518)
Affinity DataIC50: 60nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCalcium-dependent protein kinase 4(Plasmodium falciparum (isolate 3D7))
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50345704(CHEMBL1231371 | CHEMBL2069957 | 1-(tert-butyl)-3-(...)
Affinity DataIC50: 177nMAssay Description:Inhibition of CDPK4 in Plasmodium falciparum 3D7 microgametesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50397592(CHEMBL2171514)
Affinity DataIC50: 240nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50397593(CHEMBL2171513)
Affinity DataIC50: 260nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50397591(CHEMBL2171515)
Affinity DataIC50: 510nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM47658(cid_1477566 | 1-(4-methylphenyl)-3-(2-pyridin-3-yl...)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50397595(CHEMBL2171512)
Affinity DataIC50: 5.30E+3nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCell division related protein kinase 2(Leishmania major)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM78336(CHEMBL1328065 | (6E)-6-[4-(3-pyridinylmethylamino)...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of Leishmania major CRK3 expressed in Escherichia coli BL21 (DE3) using 5FAM-GGGRSPGRRRRK-OH as substrate after 60 mins by IMAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 1(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50321461(2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-ph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CDK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 7(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50321461(2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-ph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CDK7More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 6(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50321461(2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-ph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CDK6More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Montclair State University

Curated by ChEMBL
LigandPNGBDBM50321461(2-bromo-N-(2,5-dichlorothiophen-3-ylsulfonyl)-N-ph...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CDK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed