Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50040729
TargetSphingosine 1-phosphate receptor 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399039(CHEMBL2178814)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human S1P1R receptor expressed in CHO cell membranes by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399039(CHEMBL2178814)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human S1P2R receptor expressed in CHO cell membranes by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399039(CHEMBL2178814)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human S1P3R receptor expressed in CHO cell membranes by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399039(CHEMBL2178814)
Affinity DataEC50: >1.00E+4nMAssay Description:Agonist activity at human S1P5R receptor expressed in CHO cell membranes by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399039(CHEMBL2178814)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at human S1P4R receptor expressed in CHO cell membranes by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399039(CHEMBL2178814)
Affinity DataKd:  0.670nMAssay Description:Competitive binding affinity to human S1P1R receptor expressed in CHO cell membranes by Schild plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399042(CHEMBL2178812)
Affinity DataIC50: 2.10nMAssay Description:Antagonist activity at human S1P1R receptor expressed in CHO cell membranes by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399045(CHEMBL2178809)
Affinity DataIC50: 2.60nMAssay Description:Antagonist activity at human S1P1R receptor expressed in CHO cell membranes by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399039(CHEMBL2178814)
Affinity DataIC50: 3.40nMAssay Description:Antagonist activity at human S1P1R receptor expressed in CHO cell membranes by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399044(CHEMBL2178810)
Affinity DataIC50: 6.10nMAssay Description:Antagonist activity at human S1P1R receptor expressed in CHO cell membranes by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399043(CHEMBL2178811)
Affinity DataIC50: 8.40nMAssay Description:Antagonist activity at human S1P1R receptor expressed in CHO cell membranes by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399041(CHEMBL2178813)
Affinity DataIC50: 12nMAssay Description:Antagonist activity at human S1P1R receptor expressed in CHO cell membranes by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399040(CHEMBL2178815)
Affinity DataIC50: 20nMAssay Description:Antagonist activity at human S1P1R receptor expressed in CHO cell membranes by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399039(CHEMBL2178814)
Affinity DataIC50: 802nMAssay Description:Antagonist activity at human S1P3R receptor expressed in CHO cell membranes by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 5(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399039(CHEMBL2178814)
Affinity DataIC50: 978nMAssay Description:Antagonist activity at human S1P5R receptor expressed in CHO cell membranes by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 4(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399039(CHEMBL2178814)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human S1P4R receptor expressed in CHO cell membranes by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Novartis Pharma

Curated by ChEMBL
LigandPNGBDBM50399039(CHEMBL2178814)
Affinity DataIC50: 1.00E+4nMAssay Description:Antagonist activity at human S1P2R receptor expressed in CHO cell membranes by [35S]GTPgamma binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed