Compile Data Set for Download or QSAR
Report error Found 25 Enz. Inhib. hit(s) with all data for entry = 50040738
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataEC50:  740nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399300(CHEMBL2180832)
Affinity DataEC50:  8.51E+3nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399299(CHEMBL2180837)
Affinity DataEC50:  6.61E+3nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399298(CHEMBL2180834)
Affinity DataEC50:  1.20E+3nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399297(CHEMBL2180838)
Affinity DataEC50:  1.17E+3nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataEC50:  1.07E+3nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399296(CHEMBL2180833)
Affinity DataEC50:  912nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399290(CHEMBL2180836)
Affinity DataEC50:  912nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399295(CHEMBL2180841)
Affinity DataEC50:  832nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataEC50:  741nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399294(CHEMBL2180840)
Affinity DataEC50:  468nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399289(CHEMBL2180835)
Affinity DataEC50:  417nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399293(CHEMBL2086582)
Affinity DataEC50:  126nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-7(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human alpha7 nAchR by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataEC50:  1.07E+4nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells by patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399291(CHEMBL2180839)
Affinity DataEC50: >3.16E+4nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in rat GH4C1 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399295(CHEMBL2180841)
Affinity DataIC50: 1.29E+3nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399294(CHEMBL2180840)
Affinity DataIC50: 3.08E+3nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399289(CHEMBL2180835)
Affinity DataIC50: 4.61E+3nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399290(CHEMBL2180836)
Affinity DataIC50: 7.94E+3nMAssay Description:Agonist activity at alpha3 nAchR in human SH-SY5Y cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataIC50: 1.58E+4nMAssay Description:Inhibition of human ERG expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399290(CHEMBL2180836)
Affinity DataIC50: 3.16E+4nMAssay Description:Agonist activity at human 5HT3R expressed in HEK293 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 3A(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399289(CHEMBL2180835)
Affinity DataIC50: 3.16E+4nMAssay Description:Agonist activity at human 5HT3R expressed in HEK293 cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-3(Human)
Siena Biotech

Curated by ChEMBL
LigandPNGBDBM50399289(CHEMBL2180835)
Affinity DataIC50: 3.16E+4nMAssay Description:Agonist activity at alpha3 nAchR in human SH-SY5Y cells assessed as stimulation of calcium flux by FLIPRMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399292(CHEMBL2180842)
Affinity DataKi:  390nMAssay Description:Displacement of [3H]-epibatidine from rat alpha7 nAchR expressed in rat GH4C1 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed