Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50040967
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50156760(2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...)
Affinity DataIC50: 4.01E+4nMT: 2°CAssay Description:Inhibition of human recombinant SIRT1 using Arg-His-Lys-Lys(epsilon-acetyl)-AMC at room temperature for 45 mins by fluorescent screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50156760(2-((2-hydroxynaphthalen-1-yl)methyleneamino)-N-(1-...)
Affinity DataIC50: 4.58E+4nMAssay Description:Inhibition of human recombinant SIRT2 using Arg-His-Lys-Lys(epsilon-acetyl)-AMC at 37 degC for 45 mins by fluorescent screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50403018(CHEMBL2207877)
Affinity DataIC50: 3.70E+6nMT: 2°CAssay Description:Inhibition of human recombinant SIRT1 using Arg-His-Lys-Lys(epsilon-acetyl)-AMC at room temperature for 45 mins by fluorescent screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50403018(CHEMBL2207877)
Affinity DataIC50: 4.50E+6nMAssay Description:Inhibition of human recombinant SIRT2 using Arg-His-Lys-Lys(epsilon-acetyl)-AMC at 37 degC for 45 mins by fluorescent screening assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed