Compile Data Set for Download or QSAR
Report error Found 17 Enz. Inhib. hit(s) with all data for entry = 50042359
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50424584(CHEMBL2312530)
Affinity DataIC50: 20nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50193145(Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...)
Affinity DataIC50: 70nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50193145(Isoquinoline 3 | CHEMBL426560 | N-[(1-CHLORO-4-HYD...)
Affinity DataKd:  80nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50424584(CHEMBL2312530)
Affinity DataKd:  100nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50424584(CHEMBL2312530)
Affinity DataKd:  110nMAssay Description:Displacement of [13C]-2OG from catalytic domain of PHD2 (181 to 426) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM26113(pyridine-2,4-dicarboxylic acid | cid_10365 | pyrid...)
Affinity DataKd:  420nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50303766(2-oxopentanedioic acid | 2-oxoglutaric acid | alph...)
Affinity DataKd:  900nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by 1H-15N HSQC titration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataKd:  2.00E+3nMAssay Description:Displacement of [13C]-2OG from catalytic domain of PHD2 (181 to 426) (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM26113(pyridine-2,4-dicarboxylic acid | cid_10365 | pyrid...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataKd:  3.00E+3nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50396018(CHEMBL1230640)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM26106(CHEMBL90852 | Oxalylglycine | [(carboxymethyl)carb...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50396018(CHEMBL1230640)
Affinity DataKd:  6.00E+4nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM26122(FUMARIC ACID | Fumarate | (2E)-but-2-enedioic acid...)
Affinity DataKd:  2.00E+5nMAssay Description:Binding affinity to human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM26122(FUMARIC ACID | Fumarate | (2E)-but-2-enedioic acid...)
Affinity DataIC50: 2.20E+5nMAssay Description:Inhibition of human PHD2 catalytic domain (181 to 426) Mn2 expressed in Escherichia coli by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM26121(Succinic acid, 6 | butanedioic acid | Succinate | ...)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of PHD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetEgl nine homolog 1(Human)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM50244093(1-hydroxypropane-1,2,3-tricarboxylate | isocitrate...)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of PHD2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed