Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50042425
TargetHistone deacetylase 1(Human)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50425908(CHEMBL2313363)
Affinity DataIC50: 0.75nMAssay Description:Inhibition of human HDAC1 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50425909(SPIRUCHOSTATIN C)
Affinity DataIC50: 0.930nMAssay Description:Inhibition of human HDAC1 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human HDAC1 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50425908(CHEMBL2313363)
Affinity DataIC50: 240nMAssay Description:Inhibition of mouse HDAC6 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50425909(SPIRUCHOSTATIN C)
Affinity DataIC50: 320nMAssay Description:Inhibition of mouse HDAC6 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHistone deacetylase 6(Mouse)
Tohoku Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50354086(FK-228 | Istodax | ROMIDEPSIN)
Affinity DataIC50: 390nMAssay Description:Inhibition of mouse HDAC6 using Ac-KGLGK(Ac)-MCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed