Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50042513
TargetNEDD8-activating enzyme E1 regulatory subunit(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427034(CHEMBL2322194)
Affinity DataIC50: 4.70nMAssay Description:Inhibition of NAE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNEDD8-activating enzyme E1 regulatory subunit(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427035(CHEMBL2017005)
Affinity DataIC50: 10nMAssay Description:Inhibition of NAE (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNEDD8-activating enzyme E1 regulatory subunit(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427031(CHEMBL2322197)
Affinity DataIC50: 800nMAssay Description:Inhibition of NAE (unknown origin)-catalyzed NEDD8-Ubcl2 intermediate formation by densitometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme 6(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427035(CHEMBL2017005)
Affinity DataIC50: 920nMAssay Description:Inhibition of UBA6 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme 6(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427034(CHEMBL2322194)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of UBA6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSUMO-activating enzyme subunit 1(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50240436(2-hydroxy-6-pentadecylbenzoic acid | 6-(pentadecen...)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of recombinant SAE1(unknown origin)-mediated SUMOylation of RanGAP1-C2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSUMO-activating enzyme subunit 1(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50242188(6-{8(Z)-pentadecenyl}salicylic acid | Anacardic ac...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant SAE1(unknown origin)-mediated SUMOylation of RanGAP1-C2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme 7(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427035(CHEMBL2017005)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of UBA7 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNEDD8-activating enzyme E1 regulatory subunit(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427032(6,6''-Biapigenin | CHEMBL2322196)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of NAE (unknown origin) assessed as decrease in NEDD8-Ubcl2 formationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSUMO-activating enzyme subunit 1(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427035(CHEMBL2017005)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of SAE (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSUMO-activating enzyme subunit 1(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427034(CHEMBL2322194)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of SAE (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427034(CHEMBL2322194)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of ATG7 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSUMO-activating enzyme subunit 1(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427033(Kerriamycin B | CHEMBL2322195)
Affinity DataIC50: 1.17E+4nMAssay Description:Inhibition of recombinant His-tagged SAE1(unknown origin)-mediated SUMOylation of RanGAP1-C2 by immunoblotting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetNEDD8-activating enzyme E1 regulatory subunit(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427032(6,6''-Biapigenin | CHEMBL2322196)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of NAE (unknown origin)-catalyzed transthiolation of NEDD8 from NAE to Ubc12More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetUbiquitin-like modifier-activating enzyme ATG7(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50427035(CHEMBL2017005)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of ATG7 (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSUMO-activating enzyme subunit 1(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50322422(Largazole | CHEMBL1173445)
Affinity DataIC50: 4.50E+5nMAssay Description:Inhibition of human SAE by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed