Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50042515
TargetKappa-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50427044(CHEMBL2322511)
Affinity DataKi:  0.5nMAssay Description:Binding affinity to KOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50358171(CHEMBL1921847)
Affinity DataKi:  0.597nMAssay Description:Binding affinity to KOR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50358171(CHEMBL1921847)
Affinity DataKi:  16nMAssay Description:Binding affinity to human cloned MOR in presence of Na+/GDPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50012153(zyklophin)
Affinity DataKi:  30nMAssay Description:Displacement of [3H]diprenorphine from KOR (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50268463(c[L-Phe-D-pro-L-Phe-D-trp] | CHEMBL502411)
Affinity DataKi:  31nMAssay Description:Displacement of [3H]diprenorphine from rat cloned KOR expressed in CHO cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50268462(c[L-Phe-D-pro-L-Phe-L-trp] | CHEMBL506616)
Affinity DataKi:  35nMAssay Description:Displacement of [3H]diprenorphine from rat cloned KOR expressed in CHO cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50268462(c[L-Phe-D-pro-L-Phe-L-trp] | CHEMBL506616)
Affinity DataIC50: 47nMAssay Description:Displacement of [3H]Cl-977 from KOR in guinea pig brain membrane fraction after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50427044(CHEMBL2322511)
Affinity DataIC50: 77nMAssay Description:Antagonist activity at KOR (unknown origin) by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50358171(CHEMBL1921847)
Affinity DataKi:  122nMAssay Description:Binding affinity to human cloned DOR in presence of Na+/GDPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50268463(c[L-Phe-D-pro-L-Phe-D-trp] | CHEMBL502411)
Affinity DataKi:  259nMAssay Description:Displacement of [3H]DAMGO from rat cloned MOR expressed in CHO cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50268462(c[L-Phe-D-pro-L-Phe-L-trp] | CHEMBL506616)
Affinity DataIC50: 260nMAssay Description:Displacement of DAGO from MOR in guinea pig brain membrane fraction after 30 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Rat)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50268462(c[L-Phe-D-pro-L-Phe-L-trp] | CHEMBL506616)
Affinity DataKi:  619nMAssay Description:Displacement of [3H]DAMGO from rat cloned MOR expressed in CHO cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50268463(c[L-Phe-D-pro-L-Phe-D-trp] | CHEMBL502411)
Affinity DataKi:  2.91E+3nMAssay Description:Displacement of [3H]DPDPE from mouse cloned DOR expressed in CHO cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50268462(c[L-Phe-D-pro-L-Phe-L-trp] | CHEMBL506616)
Affinity DataKi:  4.15E+3nMAssay Description:Displacement of [3H]DPDPE from mouse cloned DOR expressed in CHO cells after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50012153(zyklophin)
Affinity DataKi:  5.88E+3nMAssay Description:Displacement of [3H]DAMGO from MOR (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50012153(zyklophin)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]DPDPE from DOR (unknown origin) expressed in CHO cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50427044(CHEMBL2322511)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at DOR (unknown origin) by [35S]GTPgammaS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Research Triangle Institute

Curated by ChEMBL
LigandPNGBDBM50427044(CHEMBL2322511)
Affinity DataIC50: 3.00E+4nMAssay Description:Antagonist activity at MOR (unknown origin) by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed