Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50042729
LigandPNGBDBM50430022(CHEMBL2144069)
Affinity DataIC50: 380nMAssay Description:Inhibition of wild type CRAF (unknown origin) using biotinylated MEK as substrate and MgCl2 incubated for 20 mins prior to MgCl2 addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50430022(CHEMBL2144069)
Affinity DataIC50: 2.64E+3nMAssay Description:Inhibition of human recombinant N-terminus His-tagged BRAF expressed in Sf9 cells coexpressing CDC37 using biotinylated MEK as substrate and MgCl2 in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50430021(CHEMBL2335864)
Affinity DataIC50: 5.84E+3nMAssay Description:Inhibition of wild type CRAF (unknown origin) using biotinylated MEK as substrate and MgCl2 incubated for 20 mins prior to MgCl2 addition measured af...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50430021(CHEMBL2335864)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human recombinant N-terminus His-tagged BRAF expressed in Sf9 cells coexpressing CDC37 using biotinylated MEK as substrate and MgCl2 in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed