Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50005296
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490735(DNDI1449875 | CHEMBL1863002)
Affinity DataIC50: 300nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490750(CHEMBL2334336)
Affinity DataIC50: 600nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490748(DNDI1435775 | CHEMBL1863056)
Affinity DataIC50: 810nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490744(DNDI1467768 | CHEMBL1862905)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490737(DNDI1538112 | CHEMBL1863288)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490736(DNDI1343536 | CHEMBL1863145)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490742(DNDI1460901 | CHEMBL1863462)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490743(DNDI1434940 | CHEMBL1863046)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490749(DNDI1434923 | CHEMBL1862798)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490753(DNDI1465083 | CHEMBL1863455)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490741(CHEMBL2334337)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490751(DNDI1434944 | CHEMBL1863306)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490745(DNDI1338491 | CHEMBL1863273)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490746(DNDI1388149 | CHEMBL1863393)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490752(DNDI1551253 | CHEMBL1862941)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490738(DNDI1490391 | CHEMBL1863131)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490747(DNDI1449876 | CHEMBL1863090)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490740(DNDI1467767 | CHEMBL1862938)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490739(DNDI1335908 | CHEMBL1862975)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetCytochrome P450 3A4/3A5(Human)
Epichem

Curated by ChEMBL
LigandPNGBDBM50490734(DNDI1402165 | CHEMBL1863136)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of CYP3A4/5 in human liver microsomes assessed as reduction in testosterone-beta-hydroxylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed