Compile Data Set for Download or QSAR
Report error Found 28 Enz. Inhib. hit(s) with all data for entry = 50042857
TargetProstaglandin G/H synthase 1(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)
Affinity DataIC50: 8.90nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50029600(CHEMBL42485 | 5-bromo-2-(4-fluorophenyl)-3-(4-(met...)
Affinity DataIC50: 30nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432281(CHEMBL2347671)
Affinity DataIC50: 50nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432287(CHEMBL2347677)
Affinity DataIC50: 60nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432286(CHEMBL2347667)
Affinity DataIC50: 70nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432280(CHEMBL2347672)
Affinity DataIC50: 80nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432285(CHEMBL2347668)
Affinity DataIC50: 100nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432279(CHEMBL2347673)
Affinity DataIC50: 110nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432287(CHEMBL2347677)
Affinity DataIC50: 160nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432281(CHEMBL2347671)
Affinity DataIC50: 170nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432286(CHEMBL2347667)
Affinity DataIC50: 210nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432278(CHEMBL2347674)
Affinity DataIC50: 240nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432280(CHEMBL2347672)
Affinity DataIC50: 240nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432284(CHEMBL2347669)
Affinity DataIC50: 280nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432283(CHEMBL2346675)
Affinity DataIC50: 280nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432277(CHEMBL2347675)
Affinity DataIC50: 310nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432282(CHEMBL2347670)
Affinity DataIC50: 310nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432276(CHEMBL2347676)
Affinity DataIC50: 320nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432285(CHEMBL2347668)
Affinity DataIC50: 320nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432284(CHEMBL2347669)
Affinity DataIC50: 340nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432278(CHEMBL2347674)
Affinity DataIC50: 360nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432279(CHEMBL2347673)
Affinity DataIC50: 390nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432283(CHEMBL2346675)
Affinity DataIC50: 390nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432277(CHEMBL2347675)
Affinity DataIC50: 400nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432282(CHEMBL2347670)
Affinity DataIC50: 420nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50432276(CHEMBL2347676)
Affinity DataIC50: 440nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 870nMAssay Description:Inhibition of COX2 in human blood assessed as TxB2 level after 1 hr by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
Tehran University of Medical Sciences

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 6.65E+3nMAssay Description:Inhibition of COX1 in human blood assessed as PGE2 level incubated for 15 mins prior to LPS-challenge measured after 24 hrs by enzyme immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed