Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 8432
TargetCarbonic anhydrase 9(Human)
S.G.S.I.T.S.

LigandPNGBDBM50022180(Coumarin derivative, 1b | CHEMBL12252 | 5,7-Dihydr...)
Affinity DataKi:  190nM ΔG°:  -35.7kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
S.G.S.I.T.S.

LigandPNGBDBM248070(4-Methyl-2H-benzo[g]chromen-2-one (5))
Affinity DataKi:  200nM ΔG°:  -35.5kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
S.G.S.I.T.S.

LigandPNGBDBM248069(4-Methyl-2H-benzo[h]chromen-2-one (4))
Affinity DataKi:  230nM ΔG°:  -35.2kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
S.G.S.I.T.S.

LigandPNGBDBM50022184(7,8-dihydroxy-4-methyl-2H-chromen-2-one | 7,8-Dihy...)
Affinity DataKi:  270nM ΔG°:  -34.9kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
S.G.S.I.T.S.

LigandPNGBDBM50022178(4-Methyl-7-hydroxycoumarin | 7-Hydroxy-4-methyl-2H...)
Affinity DataKi:  450nM ΔG°:  -33.7kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
S.G.S.I.T.S.

LigandPNGBDBM248070(4-Methyl-2H-benzo[g]chromen-2-one (5))
Affinity DataKi:  3.30E+3nM ΔG°:  -29.1kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
S.G.S.I.T.S.

LigandPNGBDBM50022178(4-Methyl-7-hydroxycoumarin | 7-Hydroxy-4-methyl-2H...)
Affinity DataKi:  4.30E+3nM ΔG°:  -28.5kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
S.G.S.I.T.S.

LigandPNGBDBM50022178(4-Methyl-7-hydroxycoumarin | 7-Hydroxy-4-methyl-2H...)
Affinity DataKi:  4.80E+3nM ΔG°:  -28.2kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
S.G.S.I.T.S.

LigandPNGBDBM248069(4-Methyl-2H-benzo[h]chromen-2-one (4))
Affinity DataKi:  5.50E+3nM ΔG°:  -27.9kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
S.G.S.I.T.S.

LigandPNGBDBM50022180(Coumarin derivative, 1b | CHEMBL12252 | 5,7-Dihydr...)
Affinity DataKi:  6.40E+3nM ΔG°:  -27.6kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
S.G.S.I.T.S.

LigandPNGBDBM50022184(7,8-dihydroxy-4-methyl-2H-chromen-2-one | 7,8-Dihy...)
Affinity DataKi:  6.60E+3nM ΔG°:  -27.5kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
S.G.S.I.T.S.

LigandPNGBDBM248070(4-Methyl-2H-benzo[g]chromen-2-one (5))
Affinity DataKi:  8.20E+3nM ΔG°:  -27.0kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
S.G.S.I.T.S.

LigandPNGBDBM50022180(Coumarin derivative, 1b | CHEMBL12252 | 5,7-Dihydr...)
Affinity DataKi:  8.40E+3nM ΔG°:  -26.9kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
S.G.S.I.T.S.

LigandPNGBDBM50022184(7,8-dihydroxy-4-methyl-2H-chromen-2-one | 7,8-Dihy...)
Affinity DataKi:  8.70E+3nM ΔG°:  -26.8kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
S.G.S.I.T.S.

LigandPNGBDBM248069(4-Methyl-2H-benzo[h]chromen-2-one (4))
Affinity DataKi:  9.00E+3nM ΔG°:  -26.8kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
S.G.S.I.T.S.

LigandPNGBDBM248070(4-Methyl-2H-benzo[g]chromen-2-one (5))
Affinity DataKi: >2.00E+5nM ΔG°: >-19.6kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
S.G.S.I.T.S.

LigandPNGBDBM50022184(7,8-dihydroxy-4-methyl-2H-chromen-2-one | 7,8-Dihy...)
Affinity DataKi: >2.00E+5nM ΔG°: >-19.6kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
S.G.S.I.T.S.

LigandPNGBDBM248069(4-Methyl-2H-benzo[h]chromen-2-one (4))
Affinity DataKi: >2.00E+5nM ΔG°: >-19.6kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
S.G.S.I.T.S.

LigandPNGBDBM50022178(4-Methyl-7-hydroxycoumarin | 7-Hydroxy-4-methyl-2H...)
Affinity DataKi: >2.00E+5nM ΔG°: >-19.6kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
S.G.S.I.T.S.

LigandPNGBDBM50022180(Coumarin derivative, 1b | CHEMBL12252 | 5,7-Dihydr...)
Affinity DataKi: >2.00E+5nM ΔG°: >-19.6kJ/molepH: 7.5 T: 2°CAssay Description:An applied photophysics stopped-flow instrument has been used for assaying the CA catalyzed CO2 hydration activity. Phenol red (at a concentration of...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/6/2017
Entry Details Article
PubMed