Compile Data Set for Download or QSAR
Report error Found 57 Enz. Inhib. hit(s) with all data for entry = 50042783
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430967(CHEMBL2337848)
Affinity DataIC50: 5.40nMAssay Description:Inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as remaining ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50069985({1-[(S)-(S)-1-((S)-1-Formyl-3-methyl-butylcarbamoy...)
Affinity DataIC50: 9nMAssay Description:Inhibition of chymotrypsin-like activity of proteasome beta-5 subunit in HEK293 cells using Suc-LLVY-Glo as substrate incubated for 2 hrs prior to su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteasome subunit beta type-2(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430961(CHEMBL2337844)
Affinity DataIC50: 12nMAssay Description:Inhibition of trypsin-like activity of human constitutive 20s proteasome beta-2 subunit using Boc-LRR-AMC as substrate assessed as remaining activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430968(CHEMBL2337847)
Affinity DataIC50: 14nMAssay Description:Inhibition of trypsin-like activity of human constitutive 20s proteasome beta-2 subunit using Boc-LRR-AMC as substrate assessed as remaining activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430969(CHEMBL2337846)
Affinity DataIC50: 15nMAssay Description:Inhibition of trypsin-like activity of human constitutive 20s proteasome beta-2 subunit using Boc-LRR-AMC as substrate assessed as remaining activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430970(CHEMBL2337845)
Affinity DataIC50: 16nMAssay Description:Inhibition of trypsin-like activity of human constitutive 20s proteasome beta-2 subunit using Boc-LRR-AMC as substrate assessed as remaining activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430969(CHEMBL2337846)
Affinity DataIC50: 19nMAssay Description:Inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as remaining ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430962(CHEMBL2337843)
Affinity DataIC50: 20nMAssay Description:Inhibition of trypsin-like activity of human constitutive 20s proteasome beta-2 subunit using Boc-LRR-AMC as substrate assessed as remaining activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430968(CHEMBL2337847)
Affinity DataIC50: 20nMAssay Description:Inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as remaining ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430970(CHEMBL2337845)
Affinity DataIC50: 23nMAssay Description:Inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as remaining ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430961(CHEMBL2337844)
Affinity DataIC50: 26nMAssay Description:Inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as remaining ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50370717(Epoxomicin | EPOXOMYCIN)
Affinity DataIC50: 26nMAssay Description:Inhibition of chymotrypsin-like activity of proteasome beta-5 subunit in HEK293 cells using Suc-LLVY-Glo as substrate incubated for 2 hrs prior to su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430962(CHEMBL2337843)
Affinity DataIC50: 26nMAssay Description:Inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as remaining ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430967(CHEMBL2337848)
Affinity DataIC50: 60nMAssay Description:Inhibition of postacid activity of human constitutive 20s proteasome beta-1 subunit using Z-LLE-betaNA as substrate assessed as remaining activity in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430967(CHEMBL2337848)
Affinity DataIC50: 200nMAssay Description:Inhibition of trypsin-like activity of human constitutive 20s proteasome beta-2 subunit using Boc-LRR-AMC as substrate assessed as remaining activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430964(CHEMBL2337841)
Affinity DataIC50: 252nMAssay Description:Inhibition of chymotrypsin-like activity of proteasome beta-5 subunit in HEK293 cells using Suc-LLVY-Glo as substrate incubated for 2 hrs prior to su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50370717(Epoxomicin | EPOXOMYCIN)
Affinity DataIC50: 300nMAssay Description:Inhibition of postacid activity of 20s proteasome beta-1 subunit in HEK293 cells using Z-nLPnLD-Glo as substrate incubated for 2 hrs prior to substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430968(CHEMBL2337847)
Affinity DataIC50: 336nMAssay Description:Inhibition of postacid activity of human constitutive 20s proteasome beta-1 subunit using Z-LLE-betaNA as substrate assessed as remaining activity in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430969(CHEMBL2337846)
Affinity DataIC50: 346nMAssay Description:Inhibition of postacid activity of human constitutive 20s proteasome beta-1 subunit using Z-LLE-betaNA as substrate assessed as remaining activity in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430961(CHEMBL2337844)
Affinity DataIC50: 370nMAssay Description:Inhibition of postacid activity of human constitutive 20s proteasome beta-1 subunit using Z-LLE-betaNA as substrate assessed as remaining activity in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430970(CHEMBL2337845)
Affinity DataIC50: 448nMAssay Description:Inhibition of postacid activity of human constitutive 20s proteasome beta-1 subunit using Z-LLE-betaNA as substrate assessed as remaining activity in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430964(CHEMBL2337841)
Affinity DataIC50: 460nMAssay Description:Inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as remaining ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430970(CHEMBL2337845)
Affinity DataIC50: 472nMAssay Description:Inhibition of chymotrypsin-like activity of proteasome beta-5 subunit in HEK293 cells using Suc-LLVY-Glo as substrate incubated for 2 hrs prior to su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430969(CHEMBL2337846)
Affinity DataIC50: 476nMAssay Description:Inhibition of chymotrypsin-like activity of proteasome beta-5 subunit in HEK293 cells using Suc-LLVY-Glo as substrate incubated for 2 hrs prior to su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430962(CHEMBL2337843)
Affinity DataIC50: 541nMAssay Description:Inhibition of chymotrypsin-like activity of proteasome beta-5 subunit in HEK293 cells using Suc-LLVY-Glo as substrate incubated for 2 hrs prior to su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430962(CHEMBL2337843)
Affinity DataIC50: 590nMAssay Description:Inhibition of postacid activity of human constitutive 20s proteasome beta-1 subunit using Z-LLE-betaNA as substrate assessed as remaining activity in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50069985({1-[(S)-(S)-1-((S)-1-Formyl-3-methyl-butylcarbamoy...)
Affinity DataIC50: 600nMAssay Description:Inhibition of postacid activity of 20s proteasome beta-1 subunit in HEK293 cells using Z-nLPnLD-Glo as substrate incubated for 2 hrs prior to substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProteasome subunit beta type-2(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430963(CHEMBL2337842)
Affinity DataIC50: 700nMAssay Description:Inhibition of trypsin-like activity of human constitutive 20s proteasome beta-2 subunit using Boc-LRR-AMC as substrate assessed as remaining activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430963(CHEMBL2337842)
Affinity DataIC50: 707nMAssay Description:Inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as remaining ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430961(CHEMBL2337844)
Affinity DataIC50: 756nMAssay Description:Inhibition of chymotrypsin-like activity of proteasome beta-5 subunit in HEK293 cells using Suc-LLVY-Glo as substrate incubated for 2 hrs prior to su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430964(CHEMBL2337841)
Affinity DataIC50: 867nMAssay Description:Inhibition of trypsin-like activity of human constitutive 20s proteasome beta-2 subunit using Boc-LRR-AMC as substrate assessed as remaining activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Baker's yeast)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430966(CHEMBL2337849)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of chymotrypsin-like activity of yeast 20S proteasome beta-5 subunit using Suc-LLVY-AMC as substrate measured up to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430963(CHEMBL2337842)
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibition of postacid activity of human constitutive 20s proteasome beta-1 subunit using Z-LLE-betaNA as substrate assessed as remaining activity in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430966(CHEMBL2337849)
Affinity DataIC50: 3.19E+3nMAssay Description:Inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as remaining ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430964(CHEMBL2337841)
Affinity DataIC50: 4.58E+3nMAssay Description:Inhibition of postacid activity of human constitutive 20s proteasome beta-1 subunit using Z-LLE-betaNA as substrate assessed as remaining activity in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-2(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430966(CHEMBL2337849)
Affinity DataIC50: 7.16E+3nMAssay Description:Inhibition of trypsin-like activity of human constitutive 20s proteasome beta-2 subunit using Boc-LRR-AMC as substrate assessed as remaining activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430966(CHEMBL2337849)
Affinity DataIC50: 7.97E+3nMAssay Description:Inhibition of chymotrypsin-like activity of proteasome beta-5 subunit in HEK293 cells using Suc-LLVY-Glo as substrate incubated for 2 hrs prior to su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Baker's yeast)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430965(CHEMBL2337850)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of chymotrypsin-like activity of yeast 20S proteasome beta-5 subunit using Suc-LLVY-AMC as substrate measured up to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430966(CHEMBL2337849)
Affinity DataIC50: 1.15E+4nMAssay Description:Inhibition of postacid activity of human constitutive 20s proteasome beta-1 subunit using Z-LLE-betaNA as substrate assessed as remaining activity in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430965(CHEMBL2337850)
Affinity DataIC50: 1.16E+4nMAssay Description:Inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as remaining ac...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430966(CHEMBL2337849)
Affinity DataIC50: 1.60E+4nMAssay Description:Inhibition of postacid activity of 20s proteasome beta-1 subunit in HEK293 cells using Z-nLPnLD-Glo as substrate incubated for 2 hrs prior to substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430964(CHEMBL2337841)
Affinity DataIC50: 1.73E+4nMAssay Description:Inhibition of postacid activity of 20s proteasome beta-1 subunit in HEK293 cells using Z-nLPnLD-Glo as substrate incubated for 2 hrs prior to substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-1(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430965(CHEMBL2337850)
Affinity DataIC50: 5.12E+4nMAssay Description:Inhibition of postacid activity of human constitutive 20s proteasome beta-1 subunit using Z-LLE-betaNA as substrate assessed as remaining activity in...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430967(CHEMBL2337848)
Affinity DataKi:  2.30nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430968(CHEMBL2337847)
Affinity DataKi:  6nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430962(CHEMBL2337843)
Affinity DataKi:  10nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430961(CHEMBL2337844)
Affinity DataKi:  11nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430970(CHEMBL2337845)
Affinity DataKi:  11nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430969(CHEMBL2337846)
Affinity DataKi:  11nMAssay Description:Competitive inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProteasome subunit beta type-5(Human)
University Paris 6

Curated by ChEMBL
LigandPNGBDBM50430963(CHEMBL2337842)
Affinity DataKi:  67nMAssay Description:Mixed type inhibition of chymotrypsin-like activity of human constitutive 20s proteasome beta-5 subunit using Suc-LLVY-AMC as substrate assessed as i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
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