Compile Data Set for Download or QSAR
Report error Found 20 Enz. Inhib. hit(s) with all data for entry = 50005350
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50173715((+)3-((1S,2S)-2-Dimethylaminomethyl-cyclopropyl)-1...)
Affinity DataIC50: 0.560nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50295296(cis-3-((1R,2S)-2-((dimethylamino)methyl)cyclopenty...)
Affinity DataIC50: 1.10nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491389(CHEMBL2380980)
Affinity DataIC50: 3.80nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491388(CHEMBL2380975)
Affinity DataIC50: 4.30nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491392(CHEMBL2380983)
Affinity DataIC50: 6nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491395(CHEMBL2380971)
Affinity DataIC50: 18nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491387(CHEMBL2380972)
Affinity DataIC50: 64nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491396(CHEMBL2380979)
Affinity DataIC50: 97nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491394(CHEMBL2380974)
Affinity DataIC50: 140nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491398(CHEMBL2380976)
Affinity DataIC50: 200nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491390(CHEMBL2380978)
Affinity DataIC50: 260nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491399(CHEMBL2380973)
Affinity DataIC50: 300nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491387(CHEMBL2380972)
Affinity DataIC50: 510nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491391(CHEMBL2380981)
Affinity DataIC50: 570nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491387(CHEMBL2380972)
Affinity DataIC50: 660nMAssay Description:Displacement of [3H]WIN-35428 form human DAT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491397(CHEMBL2380977)
Affinity DataIC50: 710nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent dopamine transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491388(CHEMBL2380975)
Affinity DataIC50: 750nMAssay Description:Displacement of [3H]WIN-35428 form human DAT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491393(CHEMBL2380982)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491388(CHEMBL2380975)
Affinity DataIC50: 3.70E+3nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed
TargetSodium-dependent noradrenaline transporter(Human)
Bristol-Myers Squibb Research and Development

Curated by ChEMBL
LigandPNGBDBM50491389(CHEMBL2380980)
Affinity DataIC50: 8.20E+3nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2020
Entry Details Article
PubMed