Compile Data Set for Download or QSAR
Report error Found 12 Enz. Inhib. hit(s) with all data for entry = 50042931
TargetCytochrome P450 2C9(Human)
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50433367(CHEMBL2377662)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2C9 assessed as tolbutamide hydroxylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50433366(CHEMBL2377663)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2C9 assessed as tolbutamide hydroxylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50116067(Zyvox | (S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2D6 assessed as dextromethorphan O-demethylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50433368(U-100592 | EPEREZOLID)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2D6 assessed as dextromethorphan O-demethylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50433367(CHEMBL2377662)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP1A2 assessed as ethoxyresorufin O-deethylation after 20 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50433366(CHEMBL2377663)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP1A2 assessed as ethoxyresorufin O-deethylation after 20 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50116067(Zyvox | (S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2C9 assessed as tolbutamide hydroxylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetCytochrome P450 2C9(Human)
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50433368(U-100592 | EPEREZOLID)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2C9 assessed as tolbutamide hydroxylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50116067(Zyvox | (S)-N-((3-(3-fluoro-4-morpholinophenyl)-2-...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP1A2 assessed as ethoxyresorufin O-deethylation after 20 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetCytochrome P450 1A2(Human)
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50433368(U-100592 | EPEREZOLID)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP1A2 assessed as ethoxyresorufin O-deethylation after 20 mins by fluorescence plate reader analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50433367(CHEMBL2377662)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2D6 assessed as dextromethorphan O-demethylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Research Foundation Itsuu Laboratory

Curated by ChEMBL
LigandPNGBDBM50433366(CHEMBL2377663)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2D6 assessed as dextromethorphan O-demethylation after 20 mins by LC/MS/MS analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/12/2014
Entry Details Article
PubMed