Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) with all data for entry = 5994
TargetGenome polyprotein(HCV)
University of Massachusetts Medical School

LigandPNGBDBM103840(Asu-mcP1P3)
Affinity DataIC50: 0.230nMAssay Description:NS3/4A protease was preincubated with increasing concentration of drugs in protease reaction buffer for 1 hour. Inhibition assays were performed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2014
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
University of Massachusetts Medical School

LigandPNGBDBM103839(Danoprevir)
Affinity DataIC50: 0.240nMAssay Description:NS3/4A protease was preincubated with increasing concentration of drugs in protease reaction buffer for 1 hour. Inhibition assays were performed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2014
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
University of Massachusetts Medical School

LigandPNGBDBM103841(5172-mcP1P3)
Affinity DataIC50: 0.260nMAssay Description:NS3/4A protease was preincubated with increasing concentration of drugs in protease reaction buffer for 1 hour. Inhibition assays were performed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2014
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
University of Massachusetts Medical School

LigandPNGBDBM103838(MK-5172)
Affinity DataIC50: 0.290nMAssay Description:NS3/4A protease was preincubated with increasing concentration of drugs in protease reaction buffer for 1 hour. Inhibition assays were performed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2014
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
University of Massachusetts Medical School

LigandPNGBDBM103838(MK-5172)
Affinity DataKi:  0.0600nMAssay Description:NS3/4A protease was preincubated with increasing concentration of drugs in protease reaction buffer for 1 hour. Inhibition assays were performed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2014
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
University of Massachusetts Medical School

LigandPNGBDBM103837(Dan-mcP2P4)
Affinity DataKi:  0.220nMAssay Description:NS3/4A protease was preincubated with increasing concentration of drugs in protease reaction buffer for 1 hour. Inhibition assays were performed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2014
Entry Details Article
PubMed
TargetGenome polyprotein(HCV)
University of Massachusetts Medical School

LigandPNGBDBM103836(Vaniprevir)
Affinity DataKi:  0.460nMAssay Description:NS3/4A protease was preincubated with increasing concentration of drugs in protease reaction buffer for 1 hour. Inhibition assays were performed in ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/16/2014
Entry Details Article
PubMed