Compile Data Set for Download or QSAR
Report error Found 74 Enz. Inhib. hit(s) with all data for entry = 50043065
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50347433(CHEMBL1801864)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of human Nampt after 3 hrs by counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435350(CHEMBL17289)
Affinity DataIC50: 2nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM81395(APO-866 | US20240327418, Example FK866 | US2024030...)
Affinity DataIC50: 3nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435349(CHEMBL2391585 | US11279687, Compound 208)
Affinity DataIC50: 3nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435348(CHEMBL2391572 | US11279687, Compound 439)
Affinity DataIC50: 4nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435347(CHEMBL2391557 | US11279687, Compound 105)
Affinity DataIC50: 4nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435346(CHEMBL2391574 | US11279687, Compound 442)
Affinity DataIC50: 5nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435345(CHEMBL2391565 | US11279687, Compound 104)
Affinity DataIC50: 5nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435366(CHEMBL2391568 | US11452717, Compound TableB-3.25 |...)
Affinity DataIC50: 7nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435378(CHEMBL1586371)
Affinity DataIC50: 7nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435377(CHEMBL2391570 | US11279687, Compound 47)
Affinity DataIC50: 7nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435376(CHEMBL2391573 | US11279687, Compound 229)
Affinity DataIC50: 7nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435375(CHEMBL2391560)
Affinity DataIC50: 9nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435374(CHEMBL2391564 | US11279687, Compound 103)
Affinity DataIC50: 9nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435366(CHEMBL2391568 | US11452717, Compound TableB-3.25 |...)
Affinity DataIC50: 10nMAssay Description:Competitive inhibition of Nampt (unknown origin) after 15 mins in presence of 1 uM NAMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435373(CHEMBL2391553 | US11279687, Compound 111)
Affinity DataIC50: 10nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435372(CHEMBL2391580 | US11279687, Compound 438)
Affinity DataIC50: 11nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435371(CHEMBL2391563)
Affinity DataIC50: 11nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435358(CHEMBL2391591)
Affinity DataIC50: 12nMAssay Description:Competitive inhibition of Nampt (unknown origin) after 15 mins in presence of 1 uM NAMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435370(CHEMBL2391566 | US11279687, Compound 30)
Affinity DataIC50: 12nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435366(CHEMBL2391568 | US11452717, Compound TableB-3.25 |...)
Affinity DataIC50: 13nMAssay Description:Competitive inhibition of Nampt (unknown origin) after 15 mins in presence of 5 uM NAMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435369(CHEMBL2391562 | US11279687, Compound 107)
Affinity DataIC50: 14nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435363(CHEMBL2391590)
Affinity DataIC50: 15nMAssay Description:Competitive inhibition of Nampt (unknown origin) after 15 mins in presence of 1 uM NAMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435363(CHEMBL2391590)
Affinity DataIC50: 16nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435368(CHEMBL2391577 | US11279687, Compound 195)
Affinity DataIC50: 17nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435367(CHEMBL2391554 | US11279687, Compound 114)
Affinity DataIC50: 19nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435366(CHEMBL2391568 | US11452717, Compound TableB-3.25 |...)
Affinity DataIC50: 19nMAssay Description:Competitive inhibition of Nampt (unknown origin) after 15 mins in presence of 25 uM NAMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435351(CHEMBL2391550)
Affinity DataIC50: 21nMAssay Description:Competitive inhibition of Nampt (unknown origin) after 15 mins in presence of 1 uM NAMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435365(CHEMBL2391575)
Affinity DataIC50: 24nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435364(CHEMBL2391584 | US11279687, Compound 436)
Affinity DataIC50: 24nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435363(CHEMBL2391590)
Affinity DataIC50: 24nMAssay Description:Competitive inhibition of Nampt (unknown origin) after 15 mins in presence of 5 uM NAMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435362(CHEMBL2391555 | US11279687, Compound 113)
Affinity DataIC50: 25nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435361(CHEMBL2391581 | US11279687, Compound 93)
Affinity DataIC50: 26nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435358(CHEMBL2391591)
Affinity DataIC50: 27nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435351(CHEMBL2391550)
Affinity DataIC50: 28nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435360(CHEMBL2391558 | US11279687, Compound 90)
Affinity DataIC50: 30nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435357(CHEMBL2391582 | US11279687, Compound 94)
Affinity DataIC50: 30nMAssay Description:Competitive inhibition of Nampt (unknown origin) after 15 mins in presence of 1 uM NAMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435359(CHEMBL2391567 | US11279687, Compound 46)
Affinity DataIC50: 31nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435358(CHEMBL2391591)
Affinity DataIC50: 33nMAssay Description:Competitive inhibition of Nampt (unknown origin) after 15 mins in presence of 5 uM NAMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435357(CHEMBL2391582 | US11279687, Compound 94)
Affinity DataIC50: 34nMAssay Description:Competitive inhibition of Nampt (unknown origin) after 15 mins in presence of 5 uM NAMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435357(CHEMBL2391582 | US11279687, Compound 94)
Affinity DataIC50: 39nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435391(CHEMBL2391587)
Affinity DataIC50: 41nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435390(CHEMBL2391578)
Affinity DataIC50: 49nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435363(CHEMBL2391590)
Affinity DataIC50: 51nMAssay Description:Competitive inhibition of Nampt (unknown origin) after 15 mins in presence of 25 uM NAMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435389(CHEMBL2391561)
Affinity DataIC50: 59nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435388(CHEMBL2391559 | US11279687, Compound 106)
Affinity DataIC50: 60nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435351(CHEMBL2391550)
Affinity DataIC50: 64nMAssay Description:Competitive inhibition of Nampt (unknown origin) after 15 mins in presence of 5 uM NAMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435387(CHEMBL2391576)
Affinity DataIC50: 80nMAssay Description:Inhibition of Nampt (unknown origin) using NAM/PRPP as substrate preincubated for 15 mins measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435358(CHEMBL2391591)
Affinity DataIC50: 82nMAssay Description:Competitive inhibition of Nampt (unknown origin) after 15 mins in presence of 25 uM NAMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Forma Therapeutics

Curated by ChEMBL
LigandPNGBDBM50435366(CHEMBL2391568 | US11452717, Compound TableB-3.25 |...)
Affinity DataIC50: 83nMAssay Description:Competitive inhibition of Nampt (unknown origin) after 15 mins in presence of 125 uM NAMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
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