Compile Data Set for Download or QSAR
Report error Found 13 Enz. Inhib. hit(s) with all data for entry = 50043036
TargetD(2) dopamine receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50130273(4-[3-(2-chlorophenothiazin-10-yl)propyl]-1-piperaz...)
Affinity DataIC50: 0.300nMT: 2°CAssay Description:Antagonist activity at dopamine D2 receptor (unknown origin) expressed in CHOK1 cells coexpressing Galpha15 assessed as inhibition of agonist-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50001884(8-Chloro-11-(4-methyl-piperazin-1-yl)-5H-dibenzo[b...)
Affinity DataKi:  3.80nMAssay Description:Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM55121(cid_65340 | Dopamine | SMR000059081 | 4-(2-aminoet...)
Affinity DataEC50:  6.70nMAssay Description:Agonist activity at dopamine D2 receptor (unknown origin) expressed in CHOK1 cells coexpressing Galpha15 by FLIPR assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetD(2) dopamine receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50073272(4-Methyl-7-[3-(4-phenyl-piperazin-1-yl)-propoxy]-c...)
Affinity DataKi:  11nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50404053(CHEMBL51767)
Affinity DataKi:  12nMAssay Description:Binding affinity to dopamine D2 receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50434827(CHEMBL2387260)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50434824(CHEMBL2387230)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50001885(3-{2-[4-(6-Fluoro-benzo[d]isoxazol-3-yl)-piperidin...)
Affinity DataKi:  22nMAssay Description:Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50434823(CHEMBL2387229)
Affinity DataIC50: 26nMT: 2°CAssay Description:Antagonist activity at dopamine D2 receptor (unknown origin) expressed in CHOK1 cells coexpressing Galpha15 assessed as inhibition of agonist-induced...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50434825(CHEMBL2387265)
Affinity DataKi:  38nMAssay Description:Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50434822(CHEMBL2385102)
Affinity DataKi:  550nMAssay Description:Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50434823(CHEMBL2387229)
Affinity DataKi:  1.13E+3nMAssay Description:Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistamine H1 receptor(Guinea pig)
Huazhong University of Science and Technology

Curated by ChEMBL
LigandPNGBDBM50434826(CHEMBL2387253)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]mepyramine from histamine H1 receptor in guinea pig cerebellum after 60 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed