Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 50005461
TargetRetinoic acid receptor RXR-alpha(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50492268(CHEMBL2398772)
Affinity DataEC50:  20nMAssay Description:Transactivation of human RXRalpha transfected in human 293 cells after 48 hrs by dual-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetRetinoic acid receptor RXR-alpha(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50032675(4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaph...)
Affinity DataEC50:  149nMAssay Description:Transactivation of human RXRalpha transfected in human 293 cells after 48 hrs by dual-luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of HDAC isolated from human HeLa cell nuclear extract after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase(Human)
Shenyang Pharmaceutical University

Curated by ChEMBL
LigandPNGBDBM50492268(CHEMBL2398772)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of HDAC isolated from human HeLa cell nuclear extract after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed