Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50043255
LigandPNGBDBM50438335(CHEMBL2408610)
Affinity DataIC50: 9nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438329(CHEMBL2408616)
Affinity DataIC50: 14nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438335(CHEMBL2408610)
Affinity DataIC50: 15nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438331(CHEMBL2408615)
Affinity DataIC50: 17nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438322(CHEMBL2408612)
Affinity DataIC50: 17nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438317(CHEMBL2408611)
Affinity DataIC50: 18nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438329(CHEMBL2408616)
Affinity DataIC50: 20nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438317(CHEMBL2408611)
Affinity DataIC50: 28nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438317(CHEMBL2408611)
Affinity DataIC50: 28nMAssay Description:Inhibition of TAK1 in human TOV21G cells assessed as inhibition of JNK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438330(CHEMBL2408614)
Affinity DataIC50: 31nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438330(CHEMBL2408614)
Affinity DataIC50: 43nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438331(CHEMBL2408615)
Affinity DataIC50: 45nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438316(CHEMBL2408613)
Affinity DataIC50: 110nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438316(CHEMBL2408613)
Affinity DataIC50: 130nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438325(CHEMBL2408617)
Affinity DataIC50: 150nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438322(CHEMBL2408612)
Affinity DataIC50: 160nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438335(CHEMBL2408610)
Affinity DataIC50: 160nMAssay Description:Inhibition of aurora B kinase in human HT-29 cells assessed as inhibition of histone H3 S10 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438325(CHEMBL2408617)
Affinity DataIC50: 190nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438334(CHEMBL2408726)
Affinity DataIC50: 230nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438333(CHEMBL2408721)
Affinity DataIC50: 560nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438320(CHEMBL2408734)
Affinity DataIC50: 600nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438321(CHEMBL2408731)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438332(CHEMBL2408725)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438331(CHEMBL2408615)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of aurora B kinase in human HT-29 cells assessed as inhibition of histone H3 S10 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438320(CHEMBL2408734)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438330(CHEMBL2408614)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of aurora B kinase in human HT-29 cells assessed as inhibition of histone H3 S10 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438329(CHEMBL2408616)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of aurora B kinase in human HT-29 cells assessed as inhibition of histone H3 S10 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438328(CHEMBL2408722)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438327(CHEMBL2408723)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438326(CHEMBL2408730)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438314(CHEMBL2408732)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438325(CHEMBL2408617)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of aurora B kinase in human HT-29 cells assessed as inhibition of histone H3 S10 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438324(CHEMBL2408727)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438321(CHEMBL2408731)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438323(CHEMBL2408728)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438314(CHEMBL2408732)
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438311(CHEMBL2408733)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438319(CHEMBL2408724)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438318(CHEMBL2408618)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438317(CHEMBL2408611)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of aurora B kinase in human HT-29 cells assessed as inhibition of histone H3 S10 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438316(CHEMBL2408613)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of aurora B kinase in human HT-29 cells assessed as inhibition of histone H3 S10 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438322(CHEMBL2408612)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of aurora B kinase in human HT-29 cells assessed as inhibition of histone H3 S10 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438313(CHEMBL2408735)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438315(CHEMBL2408619)
Affinity DataIC50: 1.27E+4nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438314(CHEMBL2408732)
Affinity DataIC50: 1.74E+4nMAssay Description:Inhibition of aurora B kinase in human HT-29 cells assessed as inhibition of histone H3 S10 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438320(CHEMBL2408734)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of aurora B kinase in human HT-29 cells assessed as inhibition of histone H3 S10 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetAurora kinase B(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438321(CHEMBL2408731)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of aurora B kinase in human HT-29 cells assessed as inhibition of histone H3 S10 phosphorylationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438313(CHEMBL2408735)
Affinity DataIC50: 2.28E+4nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438312(CHEMBL2408729)
Affinity DataIC50: 2.36E+4nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
LigandPNGBDBM50438311(CHEMBL2408733)
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of TAK1-TAB1 (unknown origin) by alphascreen assay in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed