Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) with all data for entry = 50001482
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50406414(CHEMBL76061)
Affinity DataKi:  2.80E+3nMAssay Description:Tested by protection experiments to demonstrate the inactivation of estradiol dehydrogenase and the kinetic parameter Ki app was reported at a concen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50015834(CHEMBL307621 | Diastereomer-7-Methyl-7-(4,4,4-trif...)
Affinity DataKi:  5.90E+4nMAssay Description:Tested for time-dependent inactivation of the enzyme that followed pseudo- first- order kinetics in the absence of NAD+ and the Ki values were report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target17-beta-hydroxysteroid dehydrogenase type 1(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50015835(CHEMBL75893 | Diastereomer-7-Methyl-7-(4,4,4-trifl...)
Affinity DataKi:  6.50E+4nMAssay Description:Tested for time-dependent inactivation of the enzyme that followed pseudo- first- order kinetics in the absence of NAD+ and the Ki values were report...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed