Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 6012
TargetAndrogen receptor(Human)
Georgia Institute of Technology

LigandPNGBDBM8885(Testosterone, 1 | (1S,2R,10R,11S,14S,15S)-14-hydro...)
Affinity DataKi:  3.20nM IC50: 4.70nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Georgia Institute of Technology

LigandPNGBDBM104030(Aryl Nilutamide HDACi analog 14e)
Affinity DataKi:  440nM IC50: 650nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Georgia Institute of Technology

LigandPNGBDBM104029(Aryl Nilutamide HDACi analog 14d)
Affinity DataKi:  460nM IC50: 690nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Georgia Institute of Technology

LigandPNGBDBM104027(Aryl Nilutamide HDACi analog 14b)
Affinity DataKi:  670nM IC50: 1.00E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Georgia Institute of Technology

LigandPNGBDBM104026(Aryl Nilutamide HDACi analog 14a)
Affinity DataKi:  720nM IC50: 1.08E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Georgia Institute of Technology

LigandPNGBDBM104028(Aryl Nilutamide HDACi analog 14c)
Affinity DataKi:  800nM IC50: 1.20E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Georgia Institute of Technology

LigandPNGBDBM104037(Alkyl Nilutamide HDACi analog 15f)
Affinity DataKi:  960nM IC50: 1.43E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Georgia Institute of Technology

LigandPNGBDBM104031(Aryl Nilutamide HDACi analog 14f)
Affinity DataKi:  1.06E+3nM IC50: 1.59E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Georgia Institute of Technology

LigandPNGBDBM50135908(CHEMBL146858 | Cyanonilutamide | 4-(4,4-Dimethyl-2...)
Affinity DataKi:  1.28E+3nM IC50: 1.91E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Georgia Institute of Technology

LigandPNGBDBM50425732(Xtandi | ENZALUTAMIDE | US10053433, FC 4.129 | US1...)
Affinity DataKi:  1.35E+3nM IC50: 2.03E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Georgia Institute of Technology

LigandPNGBDBM104036(Alkyl Nilutamide HDACi analog 15e)
Affinity DataKi:  2.37E+3nM IC50: 3.55E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Georgia Institute of Technology

LigandPNGBDBM18525(N-[4-cyano-3-(trifluoromethyl)phenyl]-3-[(4-fluoro...)
Affinity DataKi:  2.46E+3nM IC50: 3.69E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAndrogen receptor(Human)
Georgia Institute of Technology

LigandPNGBDBM104035(Alkyl Nilutamide HDACi analog 15d)
Affinity DataKi:  2.60E+3nM IC50: 3.91E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Georgia Institute of Technology

LigandPNGBDBM104034(Alkyl Nilutamide HDACi analog 15c)
Affinity DataKi:  2.68E+3nM IC50: 4.02E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Georgia Institute of Technology

LigandPNGBDBM104032(Alkyl Nilutamide HDACi analog 15a)
Affinity DataKi:  3.96E+3nM IC50: 5.93E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed
TargetAndrogen receptor(Human)
Georgia Institute of Technology

LigandPNGBDBM104033(Alkyl Nilutamide HDACi analog 15b)
Affinity DataKi:  4.48E+3nM IC50: 6.73E+3nMAssay Description:A series of dilutions of the compounds were prepared with 10% DMSO in HDAC assay buffer, and 5uL of the dilution was added to a 50uL reaction so that...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMed