Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50043209
TargetHistone deacetylase 6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50: 2.70nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50: 19nMAssay Description:Inhibition of HDAC3 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 20nMAssay Description:Inhibition of HDAC6 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50: 51nMAssay Description:Inhibition of HDAC10 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50: 86nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 132nMAssay Description:Inhibition of HDAC3 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 200nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50: 224nMAssay Description:Inhibition of HDAC11 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50: 231nMAssay Description:Inhibition of HDAC2 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 232nMAssay Description:Inhibition of HDAC2 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 306nMAssay Description:Inhibition of HDAC1 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 8(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 306nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHK(Ac)K(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPolyamine deacetylase HDAC10(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 432nMAssay Description:Inhibition of HDAC10 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHKK(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of HDAC8 (unknown origin) using fluorogenic peptide from p53 residues (379 to 382) (RHK(Ac)K(Ac)) as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50: 3.89E+3nMAssay Description:Inhibition of HDAC5 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50: 3.98E+3nMAssay Description:Inhibition of HDAC4 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50: 1.32E+4nMAssay Description:Inhibition of HDAC7 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 2.72E+4nMAssay Description:Inhibition of HDAC5 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of HDAC9 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 7.60E+4nMAssay Description:Inhibition of HDAC4 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.05E+5nMAssay Description:Inhibition of HDAC7 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetHistone deacetylase 9(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM19149(Zolinza | suberoylanilide hydroxamic acid | CHEMBL...)
Affinity DataIC50: 1.41E+5nMAssay Description:Inhibition of HDAC9 (unknown origin) using Boc-Lys(trifluoroacetyl)-AMC as substrate by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataKi:  0.260nMAssay Description:Inhibition of HDAC1 (unknown origin) by Fluor de Lys based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataKi:  0.260nMAssay Description:Inhibition of human recombinant HDAC1 using Ac-Leu-Gly-Lys(Ac)AMCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50005012(CHEMBL2408777)
Affinity DataKi:  0.620nMAssay Description:Inhibition of HDAC1 (unknown origin) by Fluor de Lys based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50005013(CHEMBL2408779)
Affinity DataKi:  0.820nMAssay Description:Inhibition of human recombinant HDAC1 using Ac-Leu-Gly-Lys(Ac)AMCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50005015(CHEMBL2408780)
Affinity DataKi:  9.80nMAssay Description:Inhibition of human recombinant HDAC1 using Ac-Leu-Gly-Lys(Ac)AMCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50005016(CHEMBL2408782)
Affinity DataKi:  23nMAssay Description:Inhibition of human recombinant HDAC1 using Ac-Leu-Gly-Lys(Ac)AMCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50005014(CHEMBL2408781)
Affinity DataKi:  35nMAssay Description:Inhibition of human recombinant HDAC1 using Ac-Leu-Gly-Lys(Ac)AMCA as substrate after 30 mins by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50005018(CHEMBL2407108)
Affinity DataKi:  45nMAssay Description:Inhibition of HDAC1 (unknown origin) by Fluor de Lys based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataKi:  138nMAssay Description:Inhibition of c-Src (unknown origin) after 10 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataKi:  138nMAssay Description:Inhibition of c-Src (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50005013(CHEMBL2408779)
Affinity DataKi:  190nMAssay Description:Inhibition of c-Src (unknown origin) after 10 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50005012(CHEMBL2408777)
Affinity DataKi:  371nMAssay Description:Inhibition of c-Src (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50005015(CHEMBL2408780)
Affinity DataKi:  407nMAssay Description:Inhibition of c-Src (unknown origin) after 10 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase HCK(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataKi:  504nMAssay Description:Inhibition of HCK (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50005017(CHEMBL2408783)
Affinity DataKi:  605nMAssay Description:Inhibition of c-Src (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50005016(CHEMBL2408782)
Affinity DataKi:  2.14E+3nMAssay Description:Inhibition of c-Src (unknown origin) after 10 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50437405(CHEMBL2408778)
Affinity DataKi:  2.35E+3nMAssay Description:Inhibition of c-Abl (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50005014(CHEMBL2408781)
Affinity DataKi:  4.30E+3nMAssay Description:Inhibition of c-Src (unknown origin) after 10 mins by fluorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetHistone deacetylase 1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50005017(CHEMBL2408783)
Affinity DataKi: >1.25E+7nMAssay Description:Inhibition of HDAC1 (unknown origin) by Fluor de Lys based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50005018(CHEMBL2407108)
Affinity DataKi: >1.25E+7nMAssay Description:Inhibition of c-Src (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed