Compile Data Set for Download or QSAR
Report error Found 72 Enz. Inhib. hit(s) with all data for entry = 50005718
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50354578(BUPRENORPHINE | US9315514, Buprenorphine | US10752...)
Affinity DataEC50:  2nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493802(CHEMBL2443272)
Affinity DataEC50:  2.5nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493833(CHEMBL2443260)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493801(CHEMBL2443256)
Affinity DataEC50:  5nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493818(Oliceridine | TRV-130 | US11124523, Comparative Co...)
Affinity DataKi:  6nMAssay Description:Binding affinity to human mu opioid receptor by radio-ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493831(CHEMBL2443255)
Affinity DataEC50:  6.30nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493818(Oliceridine | TRV-130 | US11124523, Comparative Co...)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493818(Oliceridine | TRV-130 | US11124523, Comparative Co...)
Affinity DataEC50:  8nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493805(CHEMBL2443271)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493826(CHEMBL2443269)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493810(CHEMBL2443279)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493811(CHEMBL2443278)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493808(CHEMBL2443257)
Affinity DataEC50:  16nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493819(CHEMBL2443259)
Affinity DataEC50:  25nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493807(CHEMBL2443261)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493806(CHEMBL2443254)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493825(CHEMBL2443263)
Affinity DataEC50:  32nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493821(CHEMBL2443282)
Affinity DataEC50:  40nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493823(CHEMBL2443258)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493802(CHEMBL2443272)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as beta-arrestin recruitment by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493812(CHEMBL2443268)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493818(Oliceridine | TRV-130 | US11124523, Comparative Co...)
Affinity DataEC50:  50nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as beta-arrestin recruitment by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493810(CHEMBL2443279)
Affinity DataEC50:  63nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as beta-arrestin recruitment by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493830(CHEMBL2443285)
Affinity DataEC50:  79nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493824(CHEMBL2443273)
Affinity DataEC50:  158nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493826(CHEMBL2443269)
Affinity DataEC50:  158nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as beta-arrestin recruitment by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493809(CHEMBL2443253)
Affinity DataEC50:  158nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493822(CHEMBL2443274)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493812(CHEMBL2443268)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as beta-arrestin recruitment by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493823(CHEMBL2443258)
Affinity DataEC50:  200nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as beta-arrestin recruitment by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493815(CHEMBL2443284)
Affinity DataEC50:  251nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493811(CHEMBL2443278)
Affinity DataEC50:  251nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as beta-arrestin recruitment by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493807(CHEMBL2443261)
Affinity DataEC50:  316nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as beta-arrestin recruitment by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493801(CHEMBL2443256)
Affinity DataEC50:  398nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as beta-arrestin recruitment by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493832(CHEMBL2443265)
Affinity DataEC50:  398nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493825(CHEMBL2443263)
Affinity DataEC50:  398nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as beta-arrestin recruitment by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50000092(Analog of 14-(Arylhydroxyamino)codeinone | 4-methy...)
Affinity DataEC50:  501nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as beta-arrestin recruitment by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493833(CHEMBL2443260)
Affinity DataEC50:  501nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as beta-arrestin recruitment by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493803(CHEMBL2443280)
Affinity DataEC50:  501nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493804(CHEMBL2443264)
Affinity DataEC50:  501nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493814(CHEMBL2443266)
Affinity DataEC50:  501nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493828(CHEMBL2443276)
Affinity DataEC50:  631nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493830(CHEMBL2443285)
Affinity DataEC50:  631nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as beta-arrestin recruitment by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493827(CHEMBL2443270)
Affinity DataEC50:  631nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493819(CHEMBL2443259)
Affinity DataEC50:  631nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as beta-arrestin recruitment by chemiluminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493811(CHEMBL2443278)
Affinity DataEC50:  750nMAssay Description:Agonist activity at human delta opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493820(CHEMBL2443277)
Affinity DataEC50:  794nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493811(CHEMBL2443278)
Affinity DataEC50:  900nMAssay Description:Agonist activity at human kappa opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluores...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Trevena

Curated by ChEMBL
LigandPNGBDBM50493829(CHEMBL2443267)
Affinity DataEC50:  1.00E+3nMAssay Description:Agonist activity at human mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-stimulated cAMP accumulation by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
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