Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with all data for entry = 50043530
TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50442525(CHEMBL2440659 | US8796295, Table 2: Compound: 1)
Affinity DataKi:  6.80nMAssay Description:Displacement of [3H]3-methoxy-5-(pyridin-2-ylethynyl)pyridine from mGlu5 receptor allosteric binding site (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Vanderbilt University Medical Center

Curated by ChEMBL
LigandPNGBDBM50442525(CHEMBL2440659 | US8796295, Table 2: Compound: 1)
Affinity DataIC50: 49nMAssay Description:Allosteric modulation of human mGlu5 receptor expressed in HEK cells assessed as effect on glutamate-induced calcium mobilizationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed