Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 7752
TargetCannabinoid receptor 1(Human)
North Carolina Central University

LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKd:  2.10nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMed
TargetCannabinoid receptor 1 [T344A](Human)
North Carolina Central University

LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKd:  2.40nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMed
TargetCannabinoid receptor 1 [I341A](Human)
North Carolina Central University

LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKd:  4.40nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMed
TargetCannabinoid receptor 1 [R340A](Human)
North Carolina Central University

LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKd:  2.40nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMed
TargetCannabinoid receptor 1 [I339A](Human)
North Carolina Central University

LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKd:  3.80nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMed
TargetCannabinoid receptor 1 [D338A](Human)
North Carolina Central University

LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKd:  2.5nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMed
TargetCannabinoid receptor 1 [P221A](Human)
North Carolina Central University

LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKd:  3.80nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMed
TargetCannabinoid receptor 1 [H219A](Human)
North Carolina Central University

LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKd:  2.5nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMed
TargetCannabinoid receptor 1 [I218A](Human)
North Carolina Central University

LigandPNGBDBM21278(SR141716 | 5-(4-chlorophenyl)-1-(2,4-dichloropheny...)
Affinity DataKd:  2.5nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
North Carolina Central University

LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKd:  1.80nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1 [T344A](Human)
North Carolina Central University

LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKd:  2.90nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1 [I341A](Human)
North Carolina Central University

LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKd:  0.900nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1 [R340A](Human)
North Carolina Central University

LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKd:  1.60nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1 [I339A](Human)
North Carolina Central University

LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKd:  1.60nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1 [D338A](Human)
North Carolina Central University

LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKd:  1.30nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1 [P221A](Human)
North Carolina Central University

LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKd:  3.30nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1 [H219A](Human)
North Carolina Central University

LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKd:  1.20nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1 [I218A](Human)
North Carolina Central University

LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataKd:  1.10nMpH: 7.4Assay Description:Briefly, ~5μg of membranes were incubated at 30 °C for 60 min with [3H]CP55940 (147.9 Ci/mmol; PerkinElmer Life Sciences) or [3H]SR141716A (43 C...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)