Compile Data Set for Download or QSAR
Report error Found 15 Enz. Inhib. hit(s) with all data for entry = 50035622
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50016323(CHEMBL12094 | 2-{4-[(2,4-Diamino-5-methyl-pyrido[2...)
Affinity DataKi:  0.00212nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50016324(CHEMBL11610 | 2-{4-[(2,4-Diamino-5-methyl-pyrido[2...)
Affinity DataKi:  0.00264nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50016326(CHEMBL428862 | 2-{4-[(2,4-Diamino-5-methyl-pyrido[...)
Affinity DataKi:  0.00293nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50367055(4-Aminofolic acid | 4-Aminopteroic acid | Aminopte...)
Affinity DataKi:  0.00355nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50016325(CHEMBL275309 | 2-{4-[(2,4-Diamino-pyrido[2,3-d]pyr...)
Affinity DataKi:  0.00365nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50016322(CHEMBL262953 | 2-{4-[(2,4-Diamino-pyrido[2,3-d]pyr...)
Affinity DataKi:  0.00530nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataKi:  0.00548nMAssay Description:Compound was evaluated for inhibitory effect on dihydrofolate reductase (DHFR) from L1210 cells at Inhibitory constant (n=3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 2.64nMAssay Description:Compound was evaluated for inhibitory effect on the thymidylate synthase (TS) of Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50226277(CHEMBL273509)
Affinity DataIC50: 2.78nMAssay Description:Compound was evaluated for inhibitory effect on the thymidylate synthase (TS) of Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM18050(MTX | cid_126941 | Methotrexate | 2-[(4-{[(2,4-dia...)
Affinity DataIC50: 3.52nMAssay Description:Compound was evaluated for inhibitory effect on the dihydrofolate reductase (DHFR) of Lactobacillus casei.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50226276(CHEMBL11139)
Affinity DataIC50: 3.86nMAssay Description:Compound was evaluated for inhibitory effect on the thymidylate synthase (TS) of Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50226277(CHEMBL273509)
Affinity DataIC50: 5.98nMAssay Description:Compound was evaluated for inhibitory effect on the dihydrofolate reductase (DHFR) of Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50226276(CHEMBL11139)
Affinity DataIC50: 15.9nMAssay Description:Compound was evaluated for inhibitory effect on the dihydrofolate reductase (DHFR) of Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetThymidylate synthase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50226275(CHEMBL267104)
Affinity DataIC50: 0nMAssay Description:Compound was evaluated for inhibitory effect on the thymidylate synthase (TS) of Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed
TargetDihydrofolate reductase(Lactobacillus casei)
TBA

Curated by ChEMBL
LigandPNGBDBM50226275(CHEMBL267104)
Affinity DataIC50: 0nMAssay Description:Compound was evaluated for inhibitory effect on the dihydrofolate reductase (DHFR) of Lactobacillus caseiMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/14/2012
Entry Details Article
PubMed