Compile Data Set for Download or QSAR
Report error Found 30 Enz. Inhib. hit(s) with all data for entry = 6157
TargetDopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112632(Euonyquinone A (5))
Affinity DataIC50: 1.15E+4nMpH: 8.05 T: 2°CAssay Description:To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetDopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112633(Combrequinone B (6))
Affinity DataIC50: 2.16E+4nMpH: 8.05 T: 2°CAssay Description:To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetDopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112634(Euonyquinone B (7))
Affinity DataIC50: 5.00E+4nMpH: 8.05 T: 2°CAssay Description:To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetDopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112628(Euonydiarylpropane A (1))
Affinity DataIC50: 1.00E+5nMpH: 8.05 T: 2°CAssay Description:To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetDopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112635((+)-Euonyquinone C (9) | (−)-Euonyquinone C ...)
Affinity DataIC50: 1.00E+5nMpH: 8.05 T: 2°CAssay Description:To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetDopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112635((+)-Euonyquinone C (9) | (−)-Euonyquinone C ...)
Affinity DataIC50: 1.00E+5nMpH: 8.05 T: 2°CAssay Description:To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetDopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112629(Euonydiarylpropane B (2))
Affinity DataIC50: 1.00E+5nMpH: 8.05 T: 2°CAssay Description:To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112639(1-(2-hydroxy-4-meth-oxyphenyl)-3-(4-hydroxy-3-meth...)
Affinity DataIC50: 2.00E+5nMpH: 7.0 T: 2°CAssay Description:500 nM hCSE in optimal buffer (50 mM Hepes, pH 7.0; final concentration) was incubated with compound for 45 min in the 192-tandem-well plate before a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112640((2R)-3′,4′-Dihydroxy-7-methoxyflavan (...)
Affinity DataIC50: 2.00E+5nMpH: 7.0 T: 2°CAssay Description:500 nM hCSE in optimal buffer (50 mM Hepes, pH 7.0; final concentration) was incubated with compound for 45 min in the 192-tandem-well plate before a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112641((2R)-3′,4′-Dihydroxy-5,7-methoxyflavan...)
Affinity DataIC50: 2.00E+5nMpH: 7.0 T: 2°CAssay Description:500 nM hCSE in optimal buffer (50 mM Hepes, pH 7.0; final concentration) was incubated with compound for 45 min in the 192-tandem-well plate before a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112638(Broussonin F (11))
Affinity DataIC50: 2.00E+5nMpH: 7.0 T: 2°CAssay Description:500 nM hCSE in optimal buffer (50 mM Hepes, pH 7.0; final concentration) was incubated with compound for 45 min in the 192-tandem-well plate before a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112637(Griffithane B (10))
Affinity DataIC50: 2.00E+5nMpH: 7.0 T: 2°CAssay Description:500 nM hCSE in optimal buffer (50 mM Hepes, pH 7.0; final concentration) was incubated with compound for 45 min in the 192-tandem-well plate before a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112635((+)-Euonyquinone C (9) | (−)-Euonyquinone C ...)
Affinity DataIC50: 2.00E+5nMpH: 7.0 T: 2°CAssay Description:500 nM hCSE in optimal buffer (50 mM Hepes, pH 7.0; final concentration) was incubated with compound for 45 min in the 192-tandem-well plate before a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112635((+)-Euonyquinone C (9) | (−)-Euonyquinone C ...)
Affinity DataIC50: 2.00E+5nMpH: 7.0 T: 2°CAssay Description:500 nM hCSE in optimal buffer (50 mM Hepes, pH 7.0; final concentration) was incubated with compound for 45 min in the 192-tandem-well plate before a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112634(Euonyquinone B (7))
Affinity DataIC50: 2.00E+5nMpH: 7.0 T: 2°CAssay Description:500 nM hCSE in optimal buffer (50 mM Hepes, pH 7.0; final concentration) was incubated with compound for 45 min in the 192-tandem-well plate before a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112633(Combrequinone B (6))
Affinity DataIC50: 2.00E+5nMpH: 7.0 T: 2°CAssay Description:500 nM hCSE in optimal buffer (50 mM Hepes, pH 7.0; final concentration) was incubated with compound for 45 min in the 192-tandem-well plate before a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112632(Euonyquinone A (5))
Affinity DataIC50: 2.00E+5nMpH: 7.0 T: 2°CAssay Description:500 nM hCSE in optimal buffer (50 mM Hepes, pH 7.0; final concentration) was incubated with compound for 45 min in the 192-tandem-well plate before a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112631(Euonydiarylpropane D (4))
Affinity DataIC50: 2.00E+5nMpH: 7.0 T: 2°CAssay Description:500 nM hCSE in optimal buffer (50 mM Hepes, pH 7.0; final concentration) was incubated with compound for 45 min in the 192-tandem-well plate before a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112630(Euonydiarylpropane C (3))
Affinity DataIC50: 2.00E+5nMpH: 7.0 T: 2°CAssay Description:500 nM hCSE in optimal buffer (50 mM Hepes, pH 7.0; final concentration) was incubated with compound for 45 min in the 192-tandem-well plate before a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112629(Euonydiarylpropane B (2))
Affinity DataIC50: 2.00E+5nMpH: 7.0 T: 2°CAssay Description:500 nM hCSE in optimal buffer (50 mM Hepes, pH 7.0; final concentration) was incubated with compound for 45 min in the 192-tandem-well plate before a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112628(Euonydiarylpropane A (1))
Affinity DataIC50: 2.00E+5nMpH: 7.0 T: 2°CAssay Description:500 nM hCSE in optimal buffer (50 mM Hepes, pH 7.0; final concentration) was incubated with compound for 45 min in the 192-tandem-well plate before a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetDopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112641((2R)-3′,4′-Dihydroxy-5,7-methoxyflavan...)
Affinity DataIC50: 2.00E+5nMpH: 8.05 T: 2°CAssay Description:To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetDopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112640((2R)-3′,4′-Dihydroxy-7-methoxyflavan (...)
Affinity DataIC50: 2.00E+5nMpH: 8.05 T: 2°CAssay Description:To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetDopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112639(1-(2-hydroxy-4-meth-oxyphenyl)-3-(4-hydroxy-3-meth...)
Affinity DataIC50: 2.00E+5nMpH: 8.05 T: 2°CAssay Description:To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetDopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112638(Broussonin F (11))
Affinity DataIC50: 2.00E+5nMpH: 8.05 T: 2°CAssay Description:To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetDopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112637(Griffithane B (10))
Affinity DataIC50: 2.00E+5nMpH: 8.05 T: 2°CAssay Description:To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetDopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112631(Euonydiarylpropane D (4))
Affinity DataIC50: 2.00E+5nMpH: 8.05 T: 2°CAssay Description:To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetDopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM112630(Euonydiarylpropane C (3))
Affinity DataIC50: 2.00E+5nMpH: 8.05 T: 2°CAssay Description:To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetCystathionine gamma-lyase(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM48449(SMR000059170 | MLS000028644 | cid_38853 | 3-(3,4-D...)
Affinity DataIC50: 3.00E+6nMpH: 7.0 T: 2°CAssay Description:500 nM hCSE in optimal buffer (50 mM Hepes, pH 7.0; final concentration) was incubated with compound for 45 min in the 192-tandem-well plate before a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed
TargetDopa decarboxylase (Aromatic L-amino acid decarboxylase), isoform CRA_a(Human)
Shanghai Center For Systems Biomedicine

LigandPNGBDBM48449(SMR000059170 | MLS000028644 | cid_38853 | 3-(3,4-D...)
Affinity DataIC50: 1.20E+6nMpH: 8.05 T: 2°CAssay Description:To the wells of a 384-well polypropylene plate, 1 µL DMSO (control) or test compounds at indicated concentrations were added, followed by the ad...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2014
Entry Details Article
PubMed