Report error Found 123 Enz. Inhib. hit(s) with all data for entry = 50045069
Affinity DataIC50: 1nMAssay Description:Inverse agonist activity at human RoRc-LBD expressed in cells assessed as SRC1 to 2 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Activity at human RoRc in human Jurkat cells assessed as inhibition of IL-17 promoterMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inverse agonist activity at human RoRc-LBD expressed in cells assessed as SRC1 to 2 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Activity at human RoRc in human Jurkat cells assessed as inhibition of IL-17 promoterMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Agonist activity at RoRc-LBD (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Activity at human RoRc in human Jurkat cells assessed as inhibition of IL-17 promoterMore data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Activity at human RoRc in human Jurkat cells assessed as inhibition of IL-17 promoterMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inverse agonist activity at human RoRc-LBD expressed in cells assessed as SRC1 to 2 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inverse agonist activity at human RoRc-LBD expressed in cells assessed as SRC1 to 2 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Inverse agonist activity at human RoRc-LBD expressed in cells assessed as SRC1 to 2 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataIC50: 6nMAssay Description:Displacement of [3H2]25-hydroxycholesterol from RoRc-LBD (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: 6nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Displacement of [3H2]25-hydroxycholesterol from RoRc-LBD (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 8nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 9nMAssay Description:Activity at RoRc in mouse CD4+ T cells assessed as inhibition of IL-17 productionMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Activity at human RoRc in human Jurkat cells assessed as inhibition of IL-17 promoterMore data for this Ligand-Target Pair
Affinity DataEC50: 10nMAssay Description:Agonist activity at RoRc-LBD (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 13nMAssay Description:Agonist activity at RoRc-LBD (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 16nMAssay Description:Agonist activity at RoRc-LBD (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 reporter assayMore data for this Ligand-Target Pair
Affinity DataIC50: 16nMAssay Description:Inverse agonist activity at human RoRc-LBD expressed in cells assessed as SRC1 to 2 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: <16nMAssay Description:Inverse agonist activity at human RoRc-LBD expressed in cells assessed as SRC1 to 2 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: 19nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: 20nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: 25nMAssay Description:Activity at human RoRc in human Jurkat cells assessed as inhibition of IL-17 promoterMore data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Displacement of [3H2]25-hydroxycholesterol from RoRc-LBD (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 31nMAssay Description:Displacement of [3H2]25-hydroxycholesterol from RoRc-LBD (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 32nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: <32nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataIC50: 33nMAssay Description:Inverse agonist activity at human RoRc-LBD expressed in cells assessed as SRC1 to 2 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataIC50: 34nMAssay Description:Binding affinity to RORgamma (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 36nMAssay Description:Agonist activity at PXR (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 NR reporter cell-based assayMore data for this Ligand-Target Pair
Affinity DataEC50: 40nMAssay Description:Agonist activity at RoRc-LBD (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: <50nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: <50nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: <50nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataEC50: <50nMAssay Description:Inhibition of RORc (unknown origin) assessed as inhibition of fluorescein-D22 recruitment by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataEC50: <50nMAssay Description:Inhibition of RORc (unknown origin) assessed as inhibition of fluorescein-D22 recruitment by TR-FRET assayMore data for this Ligand-Target Pair
Affinity DataKi: 51nMAssay Description:Binding affinity to RORc (unknown origin) by radioligand binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 53nMAssay Description:Agonist activity at human RoRc-LBD expressed in CHO cells assessed as transcriptional activity by GAL4 reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 54nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataIC50: 60nMAssay Description:Binding affinity to RORgamma (unknown origin)More data for this Ligand-Target Pair
Affinity DataEC50: 68nMAssay Description:Inverse agonist activity at human RoRc-LBD fusion protein with GST expressed in BL-21 (BL3) cells assessed as SRC1 coactivator peptide recruitmentMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Displacement of [3H]T0901317 from human RoRc expressed in HepG2 cells by scintillation proximity binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 71nMAssay Description:Agonist activity at human RoRc-LBD expressed in CHO cells assessed as transcriptional activity by GAL4 reporter assayMore data for this Ligand-Target Pair
Affinity DataEC50: 89nMAssay Description:Agonist activity at RoRc (unknown origin) expressed in HEK293 cells assessed as transcriptional activity by GAL4 NR reporter cell-based assayMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:Displacement of [3H]T0901317 from human RoRc expressed in HepG2 cells by scintillation proximity binding assayMore data for this Ligand-Target Pair
Affinity DataEC50: 100nMAssay Description:Agonist activity at human RoRc-LBD expressed in Jurkat cells assessed as IL-17 reporter activity by luciferase assay in absence of anti-CD3More data for this Ligand-Target Pair
