Compile Data Set for Download or QSAR
Report error Found 16 Enz. Inhib. hit(s) with all data for entry = 50005949
TargetProstaglandin G/H synthase 1(Human)
University of Bari "A. Moro

Curated by ChEMBL
LigandPNGBDBM50153038(5-Ethyl-3,4-diphenyl-isoxazole | CHEMBL361504)
Affinity DataIC50: 50nMAssay Description:Inhibition of human platelet COX1 by whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari "A. Moro

Curated by ChEMBL
LigandPNGBDBM13065(5-(4-chlorophenyl)-1-(4-methoxyphenyl)-3-(trifluor...)
Affinity DataIC50: 77nMAssay Description:Inhibition of ovine COX1 by peroxidase activity-based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari "A. Moro

Curated by ChEMBL
LigandPNGBDBM50153036(5-Methyl-3,4-diphenyl-isoxazole | CHEMBL365033)
Affinity DataIC50: 90nMAssay Description:Inhibition of human platelet COX1 by whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari "A. Moro

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 99nMAssay Description:Inhibition of ovine COX1 by peroxidase activity-based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Bari "A. Moro

Curated by ChEMBL
LigandPNGBDBM11639(Celecoxib | CLX | Celebrex | 4-[5-(4-methylphenyl)...)
Affinity DataIC50: 280nMAssay Description:Inhibition of ovine COX2 by peroxidase activity-based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Human)
University of Bari "A. Moro

Curated by ChEMBL
LigandPNGBDBM50153040(3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazol...)
Affinity DataIC50: 500nMAssay Description:Inhibition of human platelet COX1 by whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Human)
University of Bari "A. Moro

Curated by ChEMBL
LigandPNGBDBM50084649(CHEMBL3114664)
Affinity DataIC50: 580nMAssay Description:Inhibition of COX1 in human OVCAR3 cells using [14C]arachidonic acid as substrate preincubated for 30 mins before substrate addition by radioactivity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari "A. Moro

Curated by ChEMBL
LigandPNGBDBM50084649(CHEMBL3114664)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of ovine COX1 by peroxidase activity-based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari "A. Moro

Curated by ChEMBL
LigandPNGBDBM50153038(5-Ethyl-3,4-diphenyl-isoxazole | CHEMBL361504)
Affinity DataIC50: 1.49E+3nMAssay Description:Inhibition of human monocyte COX2 by whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari "A. Moro

Curated by ChEMBL
LigandPNGBDBM50153036(5-Methyl-3,4-diphenyl-isoxazole | CHEMBL365033)
Affinity DataIC50: 2.49E+3nMAssay Description:Inhibition of human monocyte COX2 by whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Sheep)
University of Bari "A. Moro

Curated by ChEMBL
LigandPNGBDBM17638(indometacin | Indocin | 2-{1-[(4-chlorophenyl)carb...)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of ovine COX2 by peroxidase activity-based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari "A. Moro

Curated by ChEMBL
LigandPNGBDBM50084645(CHEMBL3114671)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of ovine COX1 by peroxidase activity-based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari "A. Moro

Curated by ChEMBL
LigandPNGBDBM50153040(3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazol...)
Affinity DataIC50: 2.20E+4nMAssay Description:Inhibition of ovine COX1 by peroxidase activity-based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari "A. Moro

Curated by ChEMBL
LigandPNGBDBM50084644(CHEMBL3114659)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of ovine COX1 by peroxidase activity-based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 1(Sheep)
University of Bari "A. Moro

Curated by ChEMBL
LigandPNGBDBM50084647(CHEMBL3114661)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of ovine COX1 by peroxidase activity-based colorimetric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed
TargetProstaglandin G/H synthase 2(Human)
University of Bari "A. Moro

Curated by ChEMBL
LigandPNGBDBM50153040(3-(5-Chloro-furan-2-yl)-5-methyl-4-phenyl-isoxazol...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human monocyte COX2 by whole blood assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2020
Entry Details Article
PubMed