BindingDB PrimarySearch

Report error Found 2 Enz. Inhib. hit(s) with all data for entry = 50044327

cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University

Curated by ChEMBL

BDBM31592(PF-2545920 | substituted pyrazole, 9 | US9138494, ...)

IC50: 1.30nMAssay Description:Inhibition of full-length human recombinant PDE10A using cyclic AMP as substrate by scintillation proximity assayMore data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

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Date in BDB:
2/9/2015
Entry Details Article
PubMed

cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Washington University

Curated by ChEMBL

BDBM14754(CHEMBL19224 | 1-[(3,4-dimethoxyphenyl)methyl]-6,7-...)

IC50: 36nMAssay Description:Inhibition of PDE10A (unknown origin)More data for this Ligand-Target Pair

PDB KEGG
UniProtKB/SwissProt
GoogleScholar

Purchase CHEMBL DrugBank KEGG PC cid PC sid PDB Similars

Date in BDB:
2/9/2015
Entry Details Article
PubMed PDB

3D Structure (crystal)