Compile Data Set for Download or QSAR
Report error Found 42 Enz. Inhib. hit(s) with all data for entry = 50044386
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015366(CHEMBL3264604)
Affinity DataIC50: 29nMAssay Description:Inhibition of rat testicular microsome CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015366(CHEMBL3264604)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015367(CHEMBL3264602)
Affinity DataIC50: 60nMAssay Description:Inhibition of rat testicular microsome CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015376(CHEMBL3264608)
Affinity DataIC50: 74nMAssay Description:Inhibition of human recombinant CYP17 hydroxylase activity by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015368(CHEMBL3264600)
Affinity DataIC50: 86nMAssay Description:Inhibition of rat testicular microsome CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015366(CHEMBL3264604)
Affinity DataIC50: 140nMAssay Description:Inhibition of rat testicular microsome CYP17 hydroxylase activity by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015377(CHEMBL3264605)
Affinity DataIC50: 170nMAssay Description:Inhibition of human recombinant CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015369(CHEMBL3264597)
Affinity DataIC50: 180nMAssay Description:Inhibition of rat testicular microsome CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015369(CHEMBL3264597)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015366(CHEMBL3264604)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant CYP17 hydroxylase activity by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015370(CHEMBL3264599 | US9150527, 2)
Affinity DataIC50: 290nMAssay Description:Inhibition of rat testicular microsome CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015378(CHEMBL3264606)
Affinity DataIC50: 310nMAssay Description:Inhibition of human recombinant CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015376(CHEMBL3264608)
Affinity DataIC50: 330nMAssay Description:Inhibition of human recombinant CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015371(CHEMBL3264596)
Affinity DataIC50: 430nMAssay Description:Inhibition of rat testicular microsome CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015372(CHEMBL3264603)
Affinity DataIC50: 440nMAssay Description:Inhibition of rat testicular microsome CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015381(CHEMBL3264609)
Affinity DataIC50: 570nMAssay Description:Inhibition of human recombinant CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015377(CHEMBL3264605)
Affinity DataIC50: 690nMAssay Description:Inhibition of human recombinant CYP17 hydroxylase activity by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015370(CHEMBL3264599 | US9150527, 2)
Affinity DataIC50: 770nMAssay Description:Inhibition of human hepatocyte microsome CYP3A4 using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015380(CHEMBL3264607)
Affinity DataIC50: 940nMAssay Description:Inhibition of human recombinant CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015381(CHEMBL3264609)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant CYP17 hydroxylase activity by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015366(CHEMBL3264604)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human hepatocyte microsome CYP3A4 using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015373(CHEMBL3264595)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of rat testicular microsome CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015373(CHEMBL3264595)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human hepatocyte microsome CYP3A4 using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015369(CHEMBL3264597)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of human recombinant CYP17 hydroxylase activity by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015378(CHEMBL3264606)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human recombinant CYP17 hydroxylase activity by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015379(CHEMBL3259868)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015374(CHEMBL3264601)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of rat testicular microsome CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015367(CHEMBL3264602)
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human hepatocyte microsome CYP3A4 using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015368(CHEMBL3264600)
Affinity DataIC50: 6.50E+3nMAssay Description:Inhibition of human hepatocyte microsome CYP3A4 using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Rat)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015375(CHEMBL3264598)
Affinity DataIC50: 7.10E+3nMAssay Description:Inhibition of rat testicular microsome CYP17 lyase activity using 17alpha-hydroxypregnenolone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015374(CHEMBL3264601)
Affinity DataIC50: 9.40E+3nMAssay Description:Inhibition of human hepatocyte microsome CYP3A4 using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015379(CHEMBL3259868)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant CYP17 hydroxylase activity by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetSteroid 17-alpha-hydroxylase/17,20 lyase(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015380(CHEMBL3264607)
Affinity DataIC50: 1.30E+4nMAssay Description:Inhibition of human recombinant CYP17 hydroxylase activity by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015376(CHEMBL3264608)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human hepatocyte microsome CYP3A4 using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015372(CHEMBL3264603)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human hepatocyte microsome CYP3A4 using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015377(CHEMBL3264605)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human hepatocyte microsome CYP3A4 using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015378(CHEMBL3264606)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of human hepatocyte microsome CYP3A4 using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015371(CHEMBL3264596)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human hepatocyte microsome CYP3A4 using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015369(CHEMBL3264597)
Affinity DataIC50: 5.70E+4nMAssay Description:Inhibition of human hepatocyte microsome CYP3A4 using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015379(CHEMBL3259868)
Affinity DataIC50: 8.10E+4nMAssay Description:Inhibition of human hepatocyte microsome CYP3A4 using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015375(CHEMBL3264598)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human hepatocyte microsome CYP3A4 using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Viamet Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50015380(CHEMBL3264607)
Affinity DataIC50: 1.02E+5nMAssay Description:Inhibition of human hepatocyte microsome CYP3A4 using testosterone as substrate by HPLC/MS/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMed