Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50044495
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50019121(CHEMBL3288416)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50019126(CHEMBL3288421)
Affinity DataIC50: 7.30nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50019118(CHEMBL3288413)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50019117(CHEMBL3288412)
Affinity DataIC50: 9.10nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50019119(CHEMBL3288414)
Affinity DataIC50: 9.20nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50019129(CHEMBL3288424)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50019120(CHEMBL3288415)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50019127(CHEMBL3288422)
Affinity DataIC50: 28nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50019123(CHEMBL3288418)
Affinity DataIC50: 37nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50019116(CHEMBL3288411)
Affinity DataIC50: 92nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50019124(CHEMBL3288419)
Affinity DataIC50: 97nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50019128(CHEMBL3288423)
Affinity DataIC50: 111nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50019125(CHEMBL3288420)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50019115(CHEMBL3288410)
Affinity DataIC50: 210nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50019122(CHEMBL3288417)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50019113(CHEMBL3288408)
Affinity DataIC50: 590nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50019130(CHEMBL3288425)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Yamanouchi Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50019114(CHEMBL3288409)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of human recombinant PDE10A expressed in Sf9 insect cell system assessed as inhibition of cAMP hydrolysis preincubated for 30 mins before ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed