Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) with all data for entry = 50044510
TargetMuscarinic acetylcholine receptor M1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50313638(1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-c...)
Affinity DataEC50:  170nMAssay Description:Activation of human M1 mAChR expressed in FlpIn-CHO cells assessed as FBS-induced ERK1/2 phosphorylation incubated for 5 mins by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50313638(1-(4-methoxybenzyl)-4-oxo-1,4-dihydroquinoline-3-c...)
Affinity DataEC50:  170nMAssay Description:Activation of human M1 mAChR expressed in FlpIn-CHO cells assessed as FBS-induced ERK1/2 phosphorylation incubated for 5 mins by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50019401(CHEMBL3290084)
Affinity DataEC50:  316nMAssay Description:Activation of human M1 mAChR expressed in FlpIn-CHO cells assessed as FBS-induced ERK1/2 phosphorylation incubated for 5 mins by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50019404(CHEMBL3290087)
Affinity DataEC50:  389nMAssay Description:Activation of human M1 mAChR expressed in FlpIn-CHO cells assessed as FBS-induced ERK1/2 phosphorylation incubated for 5 mins by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50019402(CHEMBL3290085)
Affinity DataEC50:  417nMAssay Description:Activation of human M1 mAChR expressed in FlpIn-CHO cells assessed as FBS-induced ERK1/2 phosphorylation incubated for 5 mins by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetMuscarinic acetylcholine receptor M1(Human)
Monash University (Parkville Campus)

Curated by ChEMBL
LigandPNGBDBM50019403(CHEMBL3290086)
Affinity DataEC50:  1.59E+3nMAssay Description:Activation of human M1 mAChR expressed in FlpIn-CHO cells assessed as FBS-induced ERK1/2 phosphorylation incubated for 5 mins by Alphascreen assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed