Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50044516
Target5-hydroxytryptamine receptor 4(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50056415(CHEMBL83954 | RS 23597 | 4-Amino-5-chloro-2-methox...)
Affinity DataIC50: 49nMAssay Description:Partial agonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as effect on serotonin-induced receptor/Gbeta1 coupling...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50019523(CHEMBL3291078)
Affinity DataIC50: 110nMAssay Description:Antagonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as inhibition of serotonin-induced receptor/Gbeta1 coupling ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50019524(CHEMBL3291079)
Affinity DataIC50: 195nMAssay Description:Partial agonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as effect on serotonin-induced receptor/Gbeta1 coupling...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50019520(CHEMBL3291075)
Affinity DataIC50: 203nMAssay Description:Antagonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as inhibition of serotonin-induced receptor/Gbeta1 coupling ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50019525(CHEMBL3291080)
Affinity DataIC50: 453nMAssay Description:Antagonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as inhibition of serotonin-induced receptor/Gbeta1 coupling ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50019522(CHEMBL3291077)
Affinity DataIC50: 916nMAssay Description:Antagonist activity at Rluc-tagged human 5HT4R expressed in human SH-SY5Y cells assessed as inhibition of serotonin-induced receptor/Gbeta1 coupling ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50056415(CHEMBL83954 | RS 23597 | 4-Amino-5-chloro-2-methox...)
Affinity DataKi:  19nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50388686(CHEMBL74656)
Affinity DataKi:  20nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50019529(CHEMBL3291085)
Affinity DataKi:  36nMAssay Description:Binding affinity to 5HT4R (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50019523(CHEMBL3291078)
Affinity DataKi:  44nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50019520(CHEMBL3291075)
Affinity DataKi:  52nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50019525(CHEMBL3291080)
Affinity DataKi:  105nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50019522(CHEMBL3291077)
Affinity DataKi:  283nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50019528(CHEMBL3291083)
Affinity DataKi:  344nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50019524(CHEMBL3291079)
Affinity DataKi:  563nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50019527(CHEMBL3291082)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50019526(CHEMBL3291081)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 4(Guinea pig)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50019521(CHEMBL3291076)
Affinity DataKi: >1.00E+3nMAssay Description:Displacement of [3H]GR113808 from Dunkin-Hartley guinea pig brain striatum 5HT4R after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed