Compile Data Set for Download or QSAR
Report error Found 50 Enz. Inhib. hit(s) with all data for entry = 50044521
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50318633(SB-742457 | 3-benzenesulfonyl-8-piperazin-1-ylquin...)
Affinity DataKi:  0.170nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 1 hr by scintillation spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019704(CHEMBL3286578)
Affinity DataKi:  0.650nMAssay Description:Displacement of [3H]raclopride from human dopamine D2L receptor expressed in CHOK1a cell membrane after 180 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50056445(lisuride, (S) | lisuride | N'-((8alpha)-9,10-Dideh...)
Affinity DataKi:  0.660nMAssay Description:Displacement of [125]iodosulpride from human recombinant dopamine D2L receptor expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019711(CHEMBL3286585)
Affinity DataKi:  0.75nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in hamster BHK cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019754(LU-AE58054 | IDALOPIRDINE)
Affinity DataKi:  0.830nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in hamster BHK cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50024204(MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]5-HT from human recombinant 5-HT2C receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50241119(CHEMBL218166 | 7-(4-Biphenyl-3-ylmethyl-piperazin-...)
Affinity DataKi:  2.30nMAssay Description:Displacement of [3H]nemonapride from dopamine D2L receptor (unknown origin) expressed in African green monkey COS7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM28583(CHEMBL431298 | SB 271046 | 5-chloro-N-[4-methoxy-3...)
Affinity DataKi:  3nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in hamster BHK cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019706(CHEMBL3286581)
Affinity DataKi:  9nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in hamster BHK cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50090524(Ro-63-0563 | 4-Amino-N-(2,6-bis-methylamino-pyridi...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 1 hr by scintillation spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM81993(Bromocriptine+ (GTP+) | BROMOCRIPTINE | Bromocript...)
Affinity DataKi:  15nMAssay Description:Displacement of [125]iodosulpride from human recombinant dopamine D2L receptor expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019707(CHEMBL3286399)
Affinity DataKi:  21nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in hamster BHK cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019700(CHEMBL3286574)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]raclopride from human dopamine D2L receptor expressed in CHOK1a cell membrane after 180 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019708(CHEMBL3286582)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in hamster BHK cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019730(CHEMBL3286591)
Affinity DataKi:  24nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in hamster BHK cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019716(CHEMBL3286590)
Affinity DataKi:  26nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in hamster BHK cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50017543(9-Methylsulfanylmethyl-7-propyl-4,6,6a,7,8,9,10,10...)
Affinity DataKi:  26nMAssay Description:Displacement of [125]iodosulpride from human recombinant dopamine D2L receptor expressed in CHO cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019712(CHEMBL3286586)
Affinity DataKi:  29nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in hamster BHK cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019714(CHEMBL3286588)
Affinity DataKi:  47nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in hamster BHK cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019701(CHEMBL3286575)
Affinity DataKi:  54nMAssay Description:Displacement of [3H]raclopride from human dopamine D2L receptor expressed in CHOK1a cell membrane after 180 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019709(CHEMBL3286583)
Affinity DataKi:  95nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in hamster BHK cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019699(CHEMBL3286573)
Affinity DataKi:  98nMAssay Description:Displacement of [3H]raclopride from human dopamine D2L receptor expressed in CHOK1a cell membrane after 180 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019697(CHEMBL3286571)
Affinity DataKi:  110nMAssay Description:Displacement of [3H]raclopride from human dopamine D2L receptor expressed in CHOK1a cell membrane after 180 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019702(CHEMBL3286576)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]raclopride from human dopamine D2L receptor expressed in CHOK1a cell membrane after 180 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019705(CHEMBL3286579)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]raclopride from human dopamine D2L receptor expressed in CHOK1a cell membrane after 180 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019757(CHEMBL3286569)
Affinity DataKi:  140nMAssay Description:Displacement of [3H]raclopride from human dopamine D2L receptor expressed in CHOK1a cell membrane after 180 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019731(CHEMBL3286592)
Affinity DataKi:  170nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in hamster BHK cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019715(CHEMBL3286589)
Affinity DataKi:  182nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in hamster BHK cells after 60 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019711(CHEMBL3286585)
Affinity DataKi:  240nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2C receptor expressed in human tsA201 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019754(LU-AE58054 | IDALOPIRDINE)
Affinity DataKi:  250nMAssay Description:Displacement of [3H]5-HT from 5-HT2C receptor (unknown origin) expressed in hamster AV12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019706(CHEMBL3286581)
Affinity DataKi:  280nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2C receptor expressed in human tsA201 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019698(CHEMBL3286572)
Affinity DataKi:  309nMAssay Description:Displacement of [3H]raclopride from human dopamine D2L receptor expressed in CHOK1a cell membrane after 180 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019714(CHEMBL3286588)
Affinity DataKi:  340nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2C receptor expressed in human tsA201 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019710(CHEMBL3286584)
Affinity DataKi:  350nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2C receptor expressed in human tsA201 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019730(CHEMBL3286591)
Affinity DataKi:  370nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2C receptor expressed in human tsA201 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019703(CHEMBL3286577)
Affinity DataKi:  450nMAssay Description:Displacement of [3H]raclopride from human dopamine D2L receptor expressed in CHOK1a cell membrane after 180 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019713(CHEMBL3286587)
Affinity DataKi:  460nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2C receptor expressed in human tsA201 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019708(CHEMBL3286582)
Affinity DataKi:  460nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2C receptor expressed in human tsA201 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019707(CHEMBL3286399)
Affinity DataKi:  470nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2C receptor expressed in human tsA201 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019758(CHEMBL3286570)
Affinity DataKi:  570nMAssay Description:Displacement of [3H]raclopride from human dopamine D2L receptor expressed in CHOK1a cell membrane after 180 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019756(CHEMBL3286568)
Affinity DataKi:  660nMAssay Description:Displacement of [3H]raclopride from human dopamine D2L receptor expressed in CHOK1a cell membrane after 180 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM28583(CHEMBL431298 | SB 271046 | 5-chloro-N-[4-methoxy-3...)
Affinity DataKi:  770nMAssay Description:Displacement of [3H]5-HT from 5-HT2C receptor (unknown origin) expressed in hamster AV12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 6(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50024204(MESULERGINE | CHEMBL12314 | 4,7-dimethyl-(6aR,9S,1...)
Affinity DataKi:  776nMAssay Description:Displacement of [3H]LSD from human 5-HT6 receptor expressed in human HeLa cells after 1 hr by scintillation spectroscopic analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019709(CHEMBL3286583)
Affinity DataKi:  780nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2C receptor expressed in human tsA201 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019716(CHEMBL3286590)
Affinity DataKi:  870nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2C receptor expressed in human tsA201 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019712(CHEMBL3286586)
Affinity DataKi:  1.10E+3nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2C receptor expressed in human tsA201 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019715(CHEMBL3286589)
Affinity DataKi:  1.20E+3nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2C receptor expressed in human tsA201 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50090524(Ro-63-0563 | 4-Amino-N-(2,6-bis-methylamino-pyridi...)
Affinity DataKi:  2.04E+3nMAssay Description:Displacement of [3H]5-HT from human recombinant 5-HT2C receptor expressed in mouse 3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019755(CHEMBL3286567)
Affinity DataKi:  2.10E+3nMAssay Description:Displacement of [3H]raclopride from human dopamine D2L receptor expressed in CHOK1a cell membrane after 180 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2C(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50019731(CHEMBL3286592)
Affinity DataKi:  2.90E+3nMAssay Description:Displacement of [3H]mesulergine from human 5-HT2C receptor expressed in human tsA201 cells after 1 hr by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/11/2015
Entry Details Article
PubMed