Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) with all data for entry = 6806
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

LigandPNGBDBM50000541(Leutrol | CHEMBL93 | N-(1-Benzo(b)thien-2-ylethyl)...)
Affinity DataIC50: 5.30E+3nMAssay Description:The enzyme activity of 5-LOX was determined fluorescence spectrophotometrically by oxidation of the substrate H2DCFDA to the highly fluorescent 2'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

LigandPNGBDBM152734(11-bromo-5-[4-(2-fluorophenyl)piperazine-1- carbon...)
Affinity DataIC50: 5.70E+3nMAssay Description:The enzyme activity of 5-LOX was determined fluorescence spectrophotometrically by oxidation of the substrate H2DCFDA to the highly fluorescent 2'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

LigandPNGBDBM152736(5-(4-benzylpiperazine-1-carbonyl)-11-bromo-8,10-di...)
Affinity DataIC50: 2.10E+4nMAssay Description:The enzyme activity of 5-LOX was determined fluorescence spectrophotometrically by oxidation of the substrate H2DCFDA to the highly fluorescent 2'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2015
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

LigandPNGBDBM152735(11-bromo-5-{4-[4-(trifluoromethoxy)phenyl]piperazi...)
Affinity DataIC50: 8.60E+4nMAssay Description:The enzyme activity of 5-LOX was determined fluorescence spectrophotometrically by oxidation of the substrate H2DCFDA to the highly fluorescent 2'...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/21/2015
Entry Details Article
PubMed