Compile Data Set for Download or QSAR
Report error Found 10 Enz. Inhib. hit(s) with all data for entry = 50034536
TargetDiacylglycerol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50355142(CHEMBL1835919)
Affinity DataIC50: 8nMAssay Description:Inhibition of DGAT1-mediated triglyceride synthesis in human HT-29 cells using [3H]glycerol as substrate after 6 hrs by beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM27947(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 16nMAssay Description:Inhibition of DGAT1-mediated triglyceride synthesis in human HT-29 cells using [3H]glycerol as substrate after 6 hrs by beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDiacylglycerol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50355142(CHEMBL1835919)
Affinity DataIC50: 19nMAssay Description:Inhibition of full length human microsomal DGAT-1 expressed in baculovirus infected insect Sf9 cells using [14C]decanoylCoA as substrate after 1.5 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50363956(CHEMBL1952025)
Affinity DataIC50: 60nMAssay Description:Inhibition of full length human microsomal DGAT-1 expressed in baculovirus infected insect Sf9 cells using [14C]decanoylCoA as substrate after 1.5 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
LigandPNGBDBM50355142(CHEMBL1835919)
Affinity DataIC50: 64nMAssay Description:Inhibition of rat DGAT-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50363956(CHEMBL1952025)
Affinity DataIC50: 71nMAssay Description:Inhibition of DGAT1-mediated triglyceride synthesis in human HT-29 cells using [3H]glycerol as substrate after 6 hrs by beta countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM27947(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 72nMAssay Description:Inhibition of full length human microsomal DGAT-1 expressed in baculovirus infected insect Sf9 cells using [14C]decanoylCoA as substrate after 1.5 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDiacylglycerol O-acyltransferase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM27947(2-[4-(4-{4-amino-7,7-dimethyl-7H-pyrimido[4,5-b][1...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human DGAT-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50355142(CHEMBL1835919)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human DGAT-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed
TargetDiacylglycerol O-acyltransferase 2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50363956(CHEMBL1952025)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human DGAT-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/23/2012
Entry Details Article
PubMed