Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) with all data for entry = 50004622
TargetAmyloid-beta precursor protein(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50484947(CHEMBL2017621)
Affinity DataKi:  2.10nMAssay Description:Displacement of [3H]Pittsburgh compound B from human Abeta1-40 after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50484946(CHEBI:66880 | (18F)AV-45 | 18F-AV-45 | AV-45 F-18 ...)
Affinity DataKi:  2.90nMAssay Description:Binding affinity to amyloid beta aggregates in postmortem human Alzheimer's disease brain homogenates after 2 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50484947(CHEMBL2017621)
Affinity DataKi:  3.20nMAssay Description:Displacement of [3H]Pittsburgh compound B from human Abeta1-42 after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50129793(N-methyl-[11C]2-(40-methylaminophenyl)-6-hydroxy b...)
Affinity DataKi:  7.70nMAssay Description:Displacement of [3H]Pittsburgh compound B from human Abeta1-42 after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Technische Universit£T M£Nchen

Curated by ChEMBL
LigandPNGBDBM50129793(N-methyl-[11C]2-(40-methylaminophenyl)-6-hydroxy b...)
Affinity DataKi:  12nMAssay Description:Displacement of [3H]Pittsburgh compound B from human Abeta1-40 after 3 hrs by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMed