Compile Data Set for Download or QSAR
Report error Found 27 Enz. Inhib. hit(s) with all data for entry = 50040386
TargetPresenilin-2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393452(CHEMBL2159511)
Affinity DataIC50: 1nMAssay Description:Inhibition of PS2 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-42 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393452(CHEMBL2159511)
Affinity DataIC50: 1.30nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393453(CHEMBL2159510)
Affinity DataIC50: 2nMAssay Description:Inhibition of PS2 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-42 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393454(CHEMBL2159509)
Affinity DataIC50: 3nMAssay Description:Inhibition of PS2 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-42 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393454(CHEMBL2159509)
Affinity DataIC50: 3nMAssay Description:Inhibition of PS2 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-42 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393453(CHEMBL2159510)
Affinity DataIC50: 3nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393452(CHEMBL2159511)
Affinity DataIC50: 4nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393453(CHEMBL2159510)
Affinity DataIC50: 5nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393457(CHEMBL2159689)
Affinity DataIC50: 6nMAssay Description:Inhibition of PS2 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-42 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393454(CHEMBL2159509)
Affinity DataIC50: 6nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393454(CHEMBL2159509)
Affinity DataIC50: 6nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393457(CHEMBL2159689)
Affinity DataIC50: 8nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393457(CHEMBL2159689)
Affinity DataIC50: 8nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393454(CHEMBL2159509)
Affinity DataIC50: 8nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393454(CHEMBL2159509)
Affinity DataIC50: 8nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393451(CHEMBL2159687)
Affinity DataIC50: 8nMAssay Description:Inhibition of PS2 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-42 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393455(CHEMBL2159691)
Affinity DataIC50: 16nMAssay Description:Inhibition of PS2 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-42 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393451(CHEMBL2159687)
Affinity DataIC50: 18nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393451(CHEMBL2159687)
Affinity DataIC50: 20nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-2(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393456(CHEMBL2159690)
Affinity DataIC50: 20nMAssay Description:Inhibition of PS2 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-42 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393455(CHEMBL2159691)
Affinity DataIC50: 22nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393456(CHEMBL2159690)
Affinity DataIC50: 24nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393455(CHEMBL2159691)
Affinity DataIC50: 37nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393452(CHEMBL2159511)
Affinity DataIC50: 46nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as notch cleavageMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393456(CHEMBL2159690)
Affinity DataIC50: 48nMAssay Description:Inhibition of PS1 gamma-secretase expressed in HEK cells harboring Awe-Lon gene assessed as reduction of amyloid beta-40 productionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393459(CHEMBL2159688)
Affinity DataIC50: 320nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPresenilin-1(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50393458(CHEMBL2159686)
Affinity DataIC50: 377nMAssay Description:Inhibition of PS1 gamma-secretase assessed as reduction of amyloid beta-40 production by membrane based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed