Compile Data Set for Download or QSAR
Report error Found 45 Enz. Inhib. hit(s) with all data for entry = 50039819
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50357192(CHEMBL1914588)
Affinity DataEC50:  64nMAssay Description:Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM85507(NSC_4488 | CAS_4394-00-7 | Niflumic acid (Hit 16) ...)
Affinity DataEC50:  4.02E+4nMAssay Description:Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactama...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM33413(benzo[7]annulene-8-carboxylic acid, 5)
Affinity DataEC50:  1.24E+4nMAssay Description:Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactama...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM4078(Elagic Acid | CHEMBL6246 | 6,7,13,14-tetrahydroxy-...)
Affinity DataEC50:  2.96E+3nMAssay Description:Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactama...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM4350((2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid ...)
Affinity DataEC50:  7.07E+4nMAssay Description:Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactama...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM80831(SMR001488689 | MLS002695908 | cid_10138 | 3,4,6a,1...)
Affinity DataEC50:  4.70E+3nMAssay Description:Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactama...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384789(CHEMBL2037378 | Laccaic acid A (LCA))
Affinity DataEC50:  5.15E+4nMAssay Description:Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactama...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50294526(CHEMBL551842 | cid_73157 | lobaric acid)
Affinity DataEC50:  1.76E+4nMAssay Description:Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactama...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384788(LAPACHOL)
Affinity DataEC50:  4.79E+4nMAssay Description:Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactama...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-...)
Affinity DataEC50:  1.12E+4nMAssay Description:Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactama...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataEC50:  1.47E+4nMAssay Description:Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactama...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50009001(CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...)
Affinity DataEC50:  2.27E+4nMAssay Description:Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactama...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataEC50:  5.93E+3nMAssay Description:Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactama...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataEC50:  3.20E+3nMAssay Description:Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactama...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50357192(CHEMBL1914588)
Affinity DataEC50:  1.76E+4nMAssay Description:Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactama...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM33413(benzo[7]annulene-8-carboxylic acid, 5)
Affinity DataEC50:  54nMAssay Description:Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM14363(5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...)
Affinity DataEC50:  160nMAssay Description:Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM14363(5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...)
Affinity DataEC50:  6.10E+3nMAssay Description:Agonist activity at GPR35 receptor in human U2OS cells coexpressing Gal4-VP16-TEV assessed as beta arrestin translocation after 5 hrs by beta lactama...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataEC50:  7.24E+3nMAssay Description:Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataEC50:  8.02E+3nMAssay Description:Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM85507(NSC_4488 | CAS_4394-00-7 | Niflumic acid (Hit 16) ...)
Affinity DataEC50:  1.15E+3nMAssay Description:Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50009001(CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...)
Affinity DataEC50:  1.03E+4nMAssay Description:Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataEC50:  3.02E+3nMAssay Description:Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-...)
Affinity DataEC50:  1.33E+3nMAssay Description:Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384788(LAPACHOL)
Affinity DataEC50:  2.84E+3nMAssay Description:Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50294526(CHEMBL551842 | cid_73157 | lobaric acid)
Affinity DataEC50:  2.39E+3nMAssay Description:Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384789(CHEMBL2037378 | Laccaic acid A (LCA))
Affinity DataEC50:  390nMAssay Description:Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM80831(SMR001488689 | MLS002695908 | cid_10138 | 3,4,6a,1...)
Affinity DataEC50:  1.11E+4nMAssay Description:Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM4350((2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid ...)
Affinity DataEC50:  9.80E+3nMAssay Description:Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM4078(Elagic Acid | CHEMBL6246 | 6,7,13,14-tetrahydroxy-...)
Affinity DataEC50:  110nMAssay Description:Agonist activity at GPR35 receptor in human HT-29 cells after 10 mins by dynamic mass redistribution assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM4078(Elagic Acid | CHEMBL6246 | 6,7,13,14-tetrahydroxy-...)
Affinity DataIC50: 100nMAssay Description:Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50357192(CHEMBL1914588)
Affinity DataIC50: 110nMAssay Description:Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM33413(benzo[7]annulene-8-carboxylic acid, 5)
Affinity DataIC50: 110nMAssay Description:Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384789(CHEMBL2037378 | Laccaic acid A (LCA))
Affinity DataIC50: 390nMAssay Description:Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM14363(5-(2-propoxyphenyl)-2H,3H,7H-[1,2,3]triazolo[4,5-d...)
Affinity DataIC50: 1.22E+3nMAssay Description:Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM85507(NSC_4488 | CAS_4394-00-7 | Niflumic acid (Hit 16) ...)
Affinity DataIC50: 1.28E+3nMAssay Description:Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM26658(2-(2,4-dihydroxyphenyl)-3,5,7-trihydroxychromen-4-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM15236(CHEMBL164 | Cannabiscetin | 3,5,7-trihydroxy-2-(3,...)
Affinity DataIC50: 2.12E+3nMAssay Description:Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50294526(CHEMBL551842 | cid_73157 | lobaric acid)
Affinity DataIC50: 4.54E+3nMAssay Description:Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50384788(LAPACHOL)
Affinity DataIC50: 4.66E+3nMAssay Description:Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-chromone;...)
Affinity DataIC50: 1.54E+4nMAssay Description:Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataIC50: 1.86E+4nMAssay Description:Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50009001(CHEMBL8260 | Baicalein | 5,6,7-Trihydroxyflavone |...)
Affinity DataIC50: 2.82E+4nMAssay Description:Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM80831(SMR001488689 | MLS002695908 | cid_10138 | 3,4,6a,1...)
Affinity DataIC50: 3.04E+4nMAssay Description:Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed
TargetG-protein coupled receptor 35(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM4350((2E)-2-cyano-3-(4-hydroxyphenyl)prop-2-enoic acid ...)
Affinity DataIC50: 3.04E+4nMAssay Description:Desensitization of GPR35 receptor in human HT-29 cells assessed as inhibition of zaprinast-induced dynamic mass redistribution after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMed