Compile Data Set for Download or QSAR
Report error Found 8 Enz. Inhib. hit(s) with all data for entry = 50040344
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50392953(CHEMBL2152353)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant renin compound treated for 10 mins before substrate addition measured after 90 mins by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM17950(CHEMBL1639 | Rasilez | (2S,4S,5S,7S)-5-amino-N-(2-...)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of human recombinant renin compound treated for 10 mins before substrate addition measured after 90 mins by fluorescence methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50392953(CHEMBL2152353)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of human plasma renin activity after 60 mins by competitive RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetRenin(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM17950(CHEMBL1639 | Rasilez | (2S,4S,5S,7S)-5-amino-N-(2-...)
Affinity DataIC50: 2.90nMAssay Description:Inhibition of human plasma renin activity after 60 mins by competitive RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetRenin(Crab-eating macaque)
TBA

Curated by ChEMBL
LigandPNGBDBM50392953(CHEMBL2152353)
Affinity DataIC50: 6.30nMAssay Description:Inhibition of cynomolgus monkey plasma renin activity after 60 mins by competitive RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetRenin(Crab-eating macaque)
TBA

Curated by ChEMBL
LigandPNGBDBM17950(CHEMBL1639 | Rasilez | (2S,4S,5S,7S)-5-amino-N-(2-...)
Affinity DataIC50: 8nMAssay Description:Inhibition of cynomolgus monkey plasma renin activity after 60 mins by competitive RIAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCathepsin D(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50392953(CHEMBL2152353)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cathepsin DMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCathepsin E(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50392953(CHEMBL2152353)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human cathepsin EMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed