Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50043615
TargetSerine/threonine-protein kinase Sgk1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50443628(CHEMBL3092468 | US9174993, 35 | US9221828, 35)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50443634(CHEMBL3092462 | US9174993, 6 | US9221828, 6)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50443633(CHEMBL3092463 | US9174993, 7 | US9221828, 7)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50443630(CHEMBL3092466 | US9174993, 15 | US9221828, 15)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50443629(CHEMBL3092467 | US9174993, 16 | US9221828, 16)
Affinity DataIC50: 2nMAssay Description:Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50443636(CHEMBL3092460 | US9174993, 1 | US9221828, 1)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50443631(CHEMBL3092465 | US9174993, 14 | US9221828, 14)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50443632(CHEMBL3092464 | US9174993, 12 | US9221828, 12)
Affinity DataIC50: 4nMAssay Description:Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50443635(CHEMBL3092461 | US9174993, 5 | US9221828, 5)
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human SGK-1 expressed in baculovirus expression system using (5(6)-carboxyfluorescein)-RPRAATF-NH2 as substrate preincubate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50443635(CHEMBL3092461 | US9174993, 5 | US9221828, 5)
Affinity DataIC50: 630nMAssay Description:Inhibition of recombinant human SGK1 (S61 to L431, S422D) expressed in human U20S cells assessed as inhibition of GSK3beta phosphorylation after 6 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50443628(CHEMBL3092468 | US9174993, 35 | US9221828, 35)
Affinity DataIC50: 690nMAssay Description:Inhibition of recombinant human SGK1 (S61 to L431, S422D) expressed in human U20S cells assessed as inhibition of GSK3beta phosphorylation after 6 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50443636(CHEMBL3092460 | US9174993, 1 | US9221828, 1)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of recombinant human SGK1 (S61 to L431, S422D) expressed in human U20S cells assessed as inhibition of GSK3beta phosphorylation after 6 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50443632(CHEMBL3092464 | US9174993, 12 | US9221828, 12)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human SGK1 (S61 to L431, S422D) expressed in human U20S cells assessed as inhibition of GSK3beta phosphorylation after 6 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50443629(CHEMBL3092467 | US9174993, 16 | US9221828, 16)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of recombinant human SGK1 (S61 to L431, S422D) expressed in human U20S cells assessed as inhibition of GSK3beta phosphorylation after 6 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50443634(CHEMBL3092462 | US9174993, 6 | US9221828, 6)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human SGK1 (S61 to L431, S422D) expressed in human U20S cells assessed as inhibition of GSK3beta phosphorylation after 6 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50443630(CHEMBL3092466 | US9174993, 15 | US9221828, 15)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of recombinant human SGK1 (S61 to L431, S422D) expressed in human U20S cells assessed as inhibition of GSK3beta phosphorylation after 6 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50443633(CHEMBL3092463 | US9174993, 7 | US9221828, 7)
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of recombinant human SGK1 (S61 to L431, S422D) expressed in human U20S cells assessed as inhibition of GSK3beta phosphorylation after 6 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase Sgk1(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50443631(CHEMBL3092465 | US9174993, 14 | US9221828, 14)
Affinity DataIC50: 2.90E+3nMAssay Description:Inhibition of recombinant human SGK1 (S61 to L431, S422D) expressed in human U20S cells assessed as inhibition of GSK3beta phosphorylation after 6 hr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed