Compile Data Set for Download or QSAR
Report error Found 18 Enz. Inhib. hit(s) with all data for entry = 50042600
TargetCytochrome P450 11B1, mitochondrial(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50378948(CHEMBL2011431 | US9394290, 36)
Affinity DataIC50: 16nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50378956(CHEMBL2011246 | US9394290, 11)
Affinity DataIC50: 17nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50378950(CHEMBL2011433 | US9394290, 38)
Affinity DataIC50: 40nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50378937(CHEMBL2011253 | US9394290, 23)
Affinity DataIC50: 42nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50378960(CHEMBL2011242 | US9394290, 5)
Affinity DataIC50: 61nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50428338(CHEMBL2331707)
Affinity DataIC50: 72nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50378969(CHEMBL2011247 | US9394290, 15)
Affinity DataIC50: 101nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50378971(CHEMBL2011248 | US9394290, 17)
Affinity DataIC50: 106nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B1, mitochondrial(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50378970(CHEMBL273205 | US9394290, 16)
Affinity DataIC50: 110nMAssay Description:Inhibition of human CYP11B1 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50378956(CHEMBL2011246 | US9394290, 11)
Affinity DataIC50: 237nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50378948(CHEMBL2011431 | US9394290, 36)
Affinity DataIC50: 251nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50378971(CHEMBL2011248 | US9394290, 17)
Affinity DataIC50: 528nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50378960(CHEMBL2011242 | US9394290, 5)
Affinity DataIC50: 911nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50378950(CHEMBL2011433 | US9394290, 38)
Affinity DataIC50: 1.16E+3nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50428338(CHEMBL2331707)
Affinity DataIC50: 1.74E+3nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50378937(CHEMBL2011253 | US9394290, 23)
Affinity DataIC50: 2.08E+3nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50378969(CHEMBL2011247 | US9394290, 15)
Affinity DataIC50: 2.11E+3nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetCytochrome P450 11B2, mitochondrial(Human)
Temple University

Curated by ChEMBL
LigandPNGBDBM50378970(CHEMBL273205 | US9394290, 16)
Affinity DataIC50: 3.41E+3nMAssay Description:Inhibition of human CYP11B2 expressed in hamster V79MZ cells using [1,2-3H]11-deoxycorticosterone as substrate preincubated for 60 mins prior to subs...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed