Compile Data Set for Download or QSAR
Report error Found 14 Enz. Inhib. hit(s) with all data for entry = 50005514
TargetAmyloid-beta precursor protein(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492522(CHEMBL2407622)
Affinity DataKi:  0.895nMAssay Description:Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492526(CHEMBL2407616)
Affinity DataKi:  0.895nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50122787(4-(6-iodoimidazo[1,2-a]pyridin-2-yl)-N,N-dimethyla...)
Affinity DataKi:  7.20nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492518(Florbetapir | US10906900, AV45)
Affinity DataKi:  13nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492516(CHEMBL2407621)
Affinity DataKi:  16nMAssay Description:Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492519(CHEMBL2407615)
Affinity DataKi:  16nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492523(CHEMBL2407623)
Affinity DataKi:  111nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492523(CHEMBL2407623)
Affinity DataKi:  111nMAssay Description:Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492517(CHEMBL2407618)
Affinity DataKi: >242nMAssay Description:Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492520(CHEMBL2407624)
Affinity DataKi:  242nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492521(CHEMBL2407617)
Affinity DataKi: >242nMAssay Description:Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492520(CHEMBL2407624)
Affinity DataKi: >242nMAssay Description:Binding affinity to beta-amyloid plaque in Alzheimer's disease patient brain cortex after 1 hr by thioflavin-S based autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492524(CHEMBL2407625)
Affinity DataKi:  758nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed
TargetAmyloid-beta precursor protein(Human)
Kyoto University

Curated by ChEMBL
LigandPNGBDBM50492525(CHEMBL2407626)
Affinity DataKi:  1.18E+3nMAssay Description:Displacement of [125I]IMPY from amyloid beta (1 to 42) (unknown origin) after 3 hrs by gamma countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PubMed